ENSMUSG00000063730


Mus musculus

Features
Gene ID: ENSMUSG00000063730
  
Biological name :Hsd3b2
  
Synonyms : Hsd3b2 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 / P26149
  
Possible biological names infered from orthology : HSD3B1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / P14060 / P26439
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 98709255
Gene end: 98724543
  
Corresponding Affymetrix probe sets: 10500547 (MoGene1.0st)   1425127_at (Mouse Genome 430 2.0 Array)   1460232_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000102635
Ensembl peptide - ENSMUSP00000102636
Ensembl peptide - ENSMUSP00000136533
NCBI entrez gene - 15493     See in Manteia.
MGI - MGI:96234
RefSeq - NM_153193
RefSeq - XM_006501038
RefSeq Peptide - NP_694873
swissprot - P26149
Ensembl - ENSMUSG00000063730
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hsd3b1ENSDARG00000069926Danio rerio
 hsd3b2ENSDARG00000019747Danio rerio
 HSD3B1ENSGALG00000037951Gallus gallus
 HSD3B1ENSG00000203857Homo sapiens
 HSD3B2ENSG00000203859Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P26150 / Hsd3b3 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 / P26439* / HSD3B1* / HSD3B2* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000006241092
O35469 / Hsd3b6 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 / P26439* / HSD3B1* / HSD3B2* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000002786991
Hsd3b1 / P24815 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 / P26439* / HSD3B2* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid del...ENSMUSG0000002787184
Q61767 / Hsd3b4 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 / HSD3B1* / P14060* / P26439* / HSD3B2* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000009514373
Q61767 / Gm10681 / predicted gene 10681 / HSD3B1* / P26439* / P14060* / HSD3B2* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2* / hydroxy-delta-5-steroid deh...ENSMUSG0000009538873
Q61694 / Hsd3b5 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 / HSD3B1* / P14060* / P26439* / HSD3B2* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and s...ENSMUSG0000003809272
Gm4450 / HSD3B2* / P26439* / HSD3B1* / P14060* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1* / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid d...ENSMUSG0000009081738
Hsd3b7 / Q9EQC1 / hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 / Q9H2F3*ENSMUSG0000004228936
Q9D665 / Sdr42e1 / short chain dehydrogenase/reductase family 42E, member 1 / Q8WUS8*ENSMUSG0000003430828
Nsdhl / Q9R1J0 / Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating / Q15738* / NAD(P) dependent steroid dehydrogenase-like*ENSMUSG0000003134927
Gm5737 / short chain dehydrogenase/reductase family 42E, member 2 / A6NKP2* / SDR42E2*ENSMUSG0000010939227


Protein motifs (from Interpro)
Interpro ID Name
 IPR002225  3-beta hydroxysteroid dehydrogenase/isomerase
 IPR036291  NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006694 steroid biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031966 mitochondrial membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity IEA
 molecular_functionGO:0004769 steroid delta-isomerase activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0102294 cholesterol dehydrogenase activity IEA


Pathways (from Reactome)
Pathway description
Androgen biosynthesis
Mineralocorticoid biosynthesis
Glucocorticoid biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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