ENSDARG00000020054


Danio rerio

Features
Gene ID: ENSDARG00000020054
  
Biological name :aox6
  
Synonyms : aldehyde oxidase 6 / aox6
  
Possible biological names infered from orthology : aldehyde oxidase 1 / Aldehyde oxidase 2 / Aldehyde oxidase 3 / Aldehyde oxidase 4 / AOX1 / Aox2 / Aox3 / Aox4 / G3X982 / Q06278 / Q3TYQ9 / Q5SGK3
  
Species: Danio rerio
  
Chr. number: 22
Strand: 1
Band:
Gene start: 14051245
Gene end: 14083583
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000043710
Ensembl peptide - ENSDARP00000136674
Ensembl peptide - ENSDARP00000119018
NCBI entrez gene - 570457     See in Manteia.
RefSeq - XM_005161699
RefSeq Peptide - NP_001265746
swissprot - F1Q5R8
swissprot - A0A0G2KW58
swissprot - Q1LVZ9
swissprot - A0A0G2KU15
ZFIN ID - ZDB-GENE-050208-742
Ensembl - ENSDARG00000020054
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AOX1ENSGALG00000008185Gallus gallus
 AOX2ENSGALG00000020876Gallus gallus
 AOX1ENSG00000138356Homo sapiens
 Aox1ENSMUSG00000063558Mus musculus
 Aox2ENSMUSG00000079554Mus musculus
 Aox3ENSMUSG00000064294Mus musculus
 Aox4ENSMUSG00000038242Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aox5 / aldehyde oxidase 5ENSDARG0000007147555
xdh / xanthine dehydrogenase / P47989* / Q00519*ENSDARG0000005524052


Protein motifs (from Interpro)
Interpro ID Name
 IPR000674  Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead
 IPR001041  2Fe-2S ferredoxin-type iron-sulfur binding domain
 IPR002346  Molybdopterin dehydrogenase, FAD-binding
 IPR002888  [2Fe-2S]-binding
 IPR005107  CO dehydrogenase flavoprotein, C-terminal
 IPR006058  2Fe-2S ferredoxin, iron-sulphur binding site
 IPR008274  Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding
 IPR012675  Beta-grasp domain superfamily
 IPR016166  FAD-binding, type 2
 IPR016167  FAD-binding, type 2, subdomain 1
 IPR016208  Aldehyde oxidase/xanthine dehydrogenase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009115 xanthine catabolic process IBA
 biological_processGO:0022900 electron transport chain IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004854 xanthine dehydrogenase activity IBA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0009055 electron transfer activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016614 oxidoreductase activity, acting on CH-OH group of donors IEA
 molecular_functionGO:0016903 oxidoreductase activity, acting on the aldehyde or oxo group of donors IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0051536 iron-sulfur cluster binding IEA
 molecular_functionGO:0051537 2 iron, 2 sulfur cluster binding IEA


Pathways (from Reactome)
Pathway description
Vitamins B6 activation to pyridoxal phosphate


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000020054 aox6 / aldehyde oxidase 6 / Aox2* / Aox4* / Aox3* / AOX1* / Q5SGK3* / G3X982* / Q06278* / Q3TYQ9* / aldehyde oxidase 1* / Aldehyde oxidase 4 * / Aldehyde oxidase 3 * / Aldehyde oxidase 2 *  / complex






 

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