ENSDARG00000020876


Danio rerio

Features
Gene ID: ENSDARG00000020876
  
Biological name :pdk2a
  
Synonyms : pdk2a / pyruvate dehydrogenase kinase, isozyme 2a
  
Possible biological names infered from orthology : PDK2 / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial / pyruvate dehydrogenase kinase 2 / Q15119 / Q9JK42
  
Species: Danio rerio
  
Chr. number: 12
Strand: -1
Band:
Gene start: 28559408
Gene end: 28570989
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000012861
NCBI entrez gene - 794083     See in Manteia.
RefSeq - XM_001332558
RefSeq - XM_021480351
swissprot - E7FD62
ZFIN ID - ZDB-GENE-120910-1
Ensembl - ENSDARG00000020876
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000045846Gallus gallus
 PDK2ENSG00000005882Homo sapiens
 Pdk2ENSMUSG00000038967Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdk2b / pyruvate dehydrogenase kinase, isozyme 2b / PDK2* / Q9JK42* / Q15119* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial *ENSDARG0000005905474
pdk4 / pyruvate dehydrogenase kinase, isozyme 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase 4* / pyruvate dehydrogenase kinase, isoenzyme 4*ENSDARG0000005484869
pdk1 / pyruvate dehydrogenase kinase, isozyme 1 / Q15118* / Q8BFP9* / pyruvate dehydrogenase kinase 1* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial *ENSDARG0000001312865
pdk3a / pyruvate dehydrogenase kinase, isozyme 3a / PDK3* / Q922H2* / Q15120* / pyruvate dehydrogenase kinase 3* / pyruvate dehydrogenase kinase, isoenzyme 3*ENSDARG0000001452763
bckdk / branched chain ketoacid dehydrogenase kinase / O14874* / O55028* / [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial *ENSDARG0000001690427
pdk3b / pyruvate dehydrogenase kinase, isozyme 3b / PDK3* / Q922H2* / Q15120* / pyruvate dehydrogenase kinase 3* / pyruvate dehydrogenase kinase, isoenzyme 3*ENSDARG0000009979126


Protein motifs (from Interpro)
Interpro ID Name
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR005467  Histidine kinase domain
 IPR018955  Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
No match


Pathways (from Reactome)
Pathway description
Regulation of pyruvate dehydrogenase (PDH) complex
Signaling by Retinoic Acid


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021346 pdhb / pyruvate dehydrogenase E1 beta subunit / P11177* / Q9D051* / Pyruvate dehydrogenase E1 component subunit beta, mitochondrial *  / reaction
 ENSDARG00000008785 dldh / dihydrolipoamide dehydrogenase / DLD* / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / reaction
 ENSDARG00000015918 dlat / dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) / P10515* / Q8BMF4* / dihydrolipoamide S-acetyltransferase* / Dihydrolipoyllysine-residue acetyl...  / reaction
 ENSDARG00000051756 pdhx / pyruvate dehydrogenase complex, component X / O00330* / Q8BKZ9* / Pyruvate dehydrogenase protein X component, mitochondrial *  / reaction






 

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