ENSDARG00000015918
Danio rerio pyruvate dlat dehydrogenase process activity complex domain acid dihydrolipoyllysine-residue acetyltransferase metabolic detection light stimulus transferase metabolism biotin lipoyl attachment -oxoacid acyltransferase catalytic -oxo lipoyl-binding site peripheral subunit-binding component single hybrid motif
Features Gene ID: ENSDARG00000015918 Biological name :dlat Synonyms : dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) / Possible biological names infered from orthology : dihydrolipoamide S-acetyltransferase / / / Species: Danio rerio Chr. number: 21 Strand: -1 Band: Gene start: 23019372 Gene end: 23035120 Corresponding Affymetrix probe sets: Dr.2810.1.S1_at (Zebrafish Array) Dr.2810.2.A1_at (Zebrafish Array) Cross references: Ensembl peptide - ENSDARP00000023098B3DIV6 ZDB-GENE-030131-2921 ENSDARG00000015918
See co-cited genes in PubMed Ortholog prediction (from Ensembl )Paralog prediction (from Ensembl ) pdhx / pyruvate dehydrogenase complex, component X / O00330* / Q8BKZ9* / Pyruvate dehydrogenase protein X component, mitochondrial * ENSDARG00000051756 28
Protein motifs (from Interpro ) IPR000089 Biotin/lipoyl attachment IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site IPR004167 Peripheral subunit-binding domain IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex IPR011053 Single hybrid motif
Gene Ontology (GO ) nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen compound metabolic process biosynthetic process cellular metabolic process primary metabolic process small molecule metabolic process organic substance metabolic process response to external stimulus detection of stimulus response to abiotic stimulus system process oxidation-reduction process nitrogen comnitrogen compound metabolic process biosyntheticbiosynthetic process cellular metcellular metabolic process primary metaprimary metabolic process small molecusmall molecule metabolic process organic subsorganic substance metabolic process response to response to external stimulus detection ofdetection of stimulus response to response to abiotic stimulus system procesystem process oxidation-reoxidation-reduction process oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activity catalytic activity, acting on a protein transferase activity oxidoreductase activityoxidoreductase activity catalytic activity, acting on a proteincatalytic activity, acting on a protein transferase activitytransferase activity cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cell organelle membrane-enclosed lumen protein-containing complex cellcell organelleorganelle membrane-enclosed lumenmembrane-enclosed lumen protein-containing complexprotein-containing complex
Pathways (from Reactome )Phenotype (from MGI , Zfin or HPO ) ZFA:0000107 eye eye quality , abnormal
Show ZFA:0000282 sensory system sensory system quality , abnormal
Show ZFA:0001094 whole organism whole organism pyruvate amount , ameliorated
Show ZFA:0009090 pigment cell pigment cell quality , abnormal
Show
Interacting proteins (from Reactome ) ENSDARG00000021346 pdhb / pyruvate dehydrogenase E1 beta subunit / P11177* / Q9D051* / Pyruvate dehydrogenase E1 component subunit beta, mitochondrial * / complex ENSDARG00000008785 dldh / dihydrolipoamide dehydrogenase / DLD* / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial * / complex ENSDARG00000020876 pdk2a / pyruvate dehydrogenase kinase, isozyme 2a / PDK2* / Q9JK42* / Q15119* / pyruvate dehydrogenase kinase 2* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial * / reaction ENSDARG00000015918 dlat / dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) / P10515* / Q8BMF4* / dihydrolipoamide S-acetyltransferase* / Dihydrolipoyllysine-residue acetyl... / complex ENSDARG00000105187 gcshb / glycine cleavage system protein H (aminomethyl carrier), b / GCSH* / P23434* / Q91WK5* / AC092718.3* / AC092718.8* / glycine cleavage system protein H* / Glycine cleavage system H p... / reaction ENSDARG00000013128 pdk1 / pyruvate dehydrogenase kinase, isozyme 1 / Q15118* / Q8BFP9* / pyruvate dehydrogenase kinase 1* / [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial * / reaction ENSDARG00000054848 pdk4 / pyruvate dehydrogenase kinase, isozyme 4 / O70571* / Q16654* / pyruvate dehydrogenase kinase 4* / pyruvate dehydrogenase kinase, isoenzyme 4* / reaction ENSDARG00000051756 pdhx / pyruvate dehydrogenase complex, component X / O00330* / Q8BKZ9* / Pyruvate dehydrogenase protein X component, mitochondrial * / complex ENSDARG00000099791 pdk3b / pyruvate dehydrogenase kinase, isozyme 3b / PDK3* / Q922H2* / Q15120* / pyruvate dehydrogenase kinase 3* / pyruvate dehydrogenase kinase, isoenzyme 3* / reaction
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