ENSDARG00000105187


Danio rerio

Features
Gene ID: ENSDARG00000105187
  
Biological name :gcshb
  
Synonyms : gcshb / glycine cleavage system protein H (aminomethyl carrier), b
  
Possible biological names infered from orthology : AC092718.3 / AC092718.8 / GCSH / Glycine cleavage system H protein, mitochondrial / glycine cleavage system protein H / P23434 / Q91WK5
  
Species: Danio rerio
  
Chr. number: 7
Strand: 1
Band:
Gene start: 67451108
Gene end: 67463021
  
Corresponding Affymetrix probe sets: Dr.6285.1.S1_at (Zebrafish Array)   NM_001002579_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000134597
NCBI entrez gene - 436852     See in Manteia.
RefSeq - NM_001002579
RefSeq Peptide - NP_001002579
swissprot - Q6DGX4
ZFIN ID - ZDB-GENE-040718-319
Ensembl - ENSDARG00000105187
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GCSHENSGALG00000032679Gallus gallus
 AC092718.3ENSG00000260643Homo sapiens
 AC092718.8ENSG00000284512Homo sapiens
 GCSHENSG00000140905Homo sapiens
 GcshENSMUSG00000034424Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gcsha / glycine cleavage system protein H (aminomethyl carrier), a / GCSH* / P23434* / Q91WK5* / AC092718.3* / AC092718.8* / glycine cleavage system protein H* / Glycine cleavage system H p...ENSDARG0000009165563


Protein motifs (from Interpro)
Interpro ID Name
 IPR002930  Glycine cleavage system H-protein
 IPR003016  2-oxo acid dehydrogenase, lipoyl-binding site
 IPR011053  Single hybrid motif
 IPR017453  Glycine cleavage system H-protein, subgroup
 IPR033753  Glycine cleavage system H-protein/Simiate


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019464 glycine decarboxylation via glycine cleavage system IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005960 glycine cleavage complex IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Glycine degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000021346 pdhb / pyruvate dehydrogenase E1 beta subunit / P11177* / Q9D051* / Pyruvate dehydrogenase E1 component subunit beta, mitochondrial *  / reaction
 ENSDARG00000008785 dldh / dihydrolipoamide dehydrogenase / DLD* / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / reaction
 ENSDARG00000015918 dlat / dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) / P10515* / Q8BMF4* / dihydrolipoamide S-acetyltransferase* / Dihydrolipoyllysine-residue acetyl...  / reaction
 ENSDARG00000014915 ndufab1b / NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1b / O14561* / NDUFAB1* / NADH:ubiquinone oxidoreductase subunit AB1*  / reaction
 ENSDARG00000022845 lias / lipoic acid synthetase / O43766* / Q99M04* / Lipoyl synthase, mitochondrial *  / reaction
 ENSDARG00000040555 bckdha / branched chain keto acid dehydrogenase E1, alpha polypeptide / P12694* / AC011462.1* / branched chain ketoacid dehydrogenase E1, alpha polypeptide*  / reaction
 ENSDARG00000010862 amt / aminomethyltransferase / P48728* / Q8CFA2* / Aminomethyltransferase, mitochondrial *  / reaction
 ENSDARG00000051756 pdhx / pyruvate dehydrogenase complex, component X / O00330* / Q8BKZ9* / Pyruvate dehydrogenase protein X component, mitochondrial *  / reaction






 

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