ENSDARG00000040555


Danio rerio

Features
Gene ID: ENSDARG00000040555
  
Biological name :bckdha
  
Synonyms : bckdha / branched chain keto acid dehydrogenase E1, alpha polypeptide
  
Possible biological names infered from orthology : AC011462.1 / branched chain ketoacid dehydrogenase E1, alpha polypeptide / P12694
  
Species: Danio rerio
  
Chr. number: 18
Strand: 1
Band:
Gene start: 36066389
Gene end: 36081908
  
Corresponding Affymetrix probe sets: Dr.3814.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000059346
NCBI entrez gene - 554124     See in Manteia.
swissprot - Q4VBU0
ZFIN ID - ZDB-GENE-050522-376
Ensembl - ENSDARG00000040555
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AC011462.1ENSG00000255730Homo sapiens
 BCKDHAENSG00000248098Homo sapiens
 BckdhaENSMUSG00000060376Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pdha1b / pyruvate dehydrogenase E1 alpha 1 subunit b / PDHA1* / PDHA2* / P08559* / P29803* / P35486* / P35487* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subun...ENSDARG0000001055523
pdha1a / pyruvate dehydrogenase E1 alpha 1 subunit a / PDHA1* / PDHA2* / P08559* / P29803* / P35486* / P35487* / pyruvate dehydrogenase E1 alpha 1* / pyruvate dehydrogenase E1 alpha 1 subun...ENSDARG0000001238721


Protein motifs (from Interpro)
Interpro ID Name
 IPR001017  Dehydrogenase, E1 component
 IPR029061  Thiamin diphosphate-binding fold
 IPR034616  2-oxoisovalerate dehydrogenase subunit alpha


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0009083 branched-chain amino acid catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0003826 alpha-ketoacid dehydrogenase activity IEA
 molecular_functionGO:0003863 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity IEA
 molecular_functionGO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor IEA


Pathways (from Reactome)
Pathway description
Glyoxylate metabolism and glycine degradation
Branched-chain amino acid catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000008785 dldh / dihydrolipoamide dehydrogenase / DLD* / O08749* / P09622* / Dihydrolipoyl dehydrogenase, mitochondrial *  / complex
 ENSDARG00000016904 bckdk / branched chain ketoacid dehydrogenase kinase / O14874* / O55028* / [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial *  / reaction
 ENSDARG00000040555 bckdha / branched chain keto acid dehydrogenase E1, alpha polypeptide / P12694* / AC011462.1* / branched chain ketoacid dehydrogenase E1, alpha polypeptide*  / complex
 ENSDARG00000105187 gcshb / glycine cleavage system protein H (aminomethyl carrier), b / GCSH* / P23434* / Q91WK5* / AC092718.3* / AC092718.8* / glycine cleavage system protein H* / Glycine cleavage system H p...  / reaction






 

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