ENSDARG00000021172


Danio rerio

Features
Gene ID: ENSDARG00000021172
  
Biological name :cyp2ad2
  
Synonyms : cyp2ad2 / cytochrome P450, family 2, subfamily AD, polypeptide 2
  
Possible biological names infered from orthology : Cyp2j11 / Cyp2j12 / Cyp2j13 / CYP2J2 / Cyp2j5 / Cyp2j6 / Cyp2j7 / Cyp2j8 / Cyp2j9 / Cytochrome P450 2J5 / Cytochrome P450 2J6 / cytochrome P450 family 2 subfamily J member 2 / cytochrome P450, family 2, subfamily j, polypeptide 11 / cytochrome P450, family 2, subfamily j, polypeptide 12 / cytochrome P450, family 2, subfamily j, polypeptide 13 / cytochrome P450, family 2, subfamily j, polypeptide 7 / cytochrome P450, family 2, subfamily j, polypeptide 8 / cytochrome P450, family 2, subfamily j, polypeptide 9 / O54749 / O54750 / P51589
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 25534669
Gene end: 25542183
  
Corresponding Affymetrix probe sets: Dr.11729.1.S1_at (Zebrafish Array)   Dr.11729.2.A1_at (Zebrafish Array)   Dr.11729.2.S1_a_at (Zebrafish Array)   NM_152954_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000018819
NCBI entrez gene - 259306     See in Manteia.
RefSeq - NM_152954
RefSeq Peptide - NP_694486
swissprot - Q98T96
ZFIN ID - ZDB-GENE-020812-2
Ensembl - ENSDARG00000021172
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000011413Gallus gallus
 CYP2J23ENSGALG00000011394Gallus gallus
 CYP2J2ENSG00000134716Homo sapiens
 Cyp2j11ENSMUSG00000066097Mus musculus
 Cyp2j12ENSMUSG00000081225Mus musculus
 Cyp2j13ENSMUSG00000028571Mus musculus
 Cyp2j5ENSMUSG00000052520Mus musculus
 Cyp2j6ENSMUSG00000052914Mus musculus
 Cyp2j7ENSMUSG00000081362Mus musculus
 Cyp2j8ENSMUSG00000082932Mus musculus
 Cyp2j9ENSMUSG00000015224Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp2ad3 / cytochrome P450, family 2, subfamily AD, polypeptide 3 / CYP2J2* / O54749* / Cyp2j5* / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54750* / Cyp2j13* / Cyp2j12* / Cyp2j11* /...ENSDARG0000002265076
cyp2ad6 / cytochrome P450, family 2, subfamily AD, polypeptide 6 / CYP2J2* / O54749* / Cyp2j5* / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54750* / Cyp2j13* / Cyp2j12* / Cyp2j11* /...ENSDARG0000004295652
cyp2p7 / cyp2p9 / cytochrome P450, family 2, subfamily P, polypeptide 7 / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j6* / Cyp2j11* / Cyp2j12* / Cyp...ENSDARG0000004298051
cyp2p8 / cytochrome P450, family 2, subfamily P, polypeptide 8 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* / C...ENSDARG0000004298251
cyp2p6 / cytochrome P450, family 2, subfamily P, polypeptide 6 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* / C...ENSDARG0000004297850
cyp2p9 / cytochrome P450, family 2, subfamily P, polypeptide 9 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* / C...ENSDARG0000002263149
cyp2n13 / cytochrome P450, family 2, subfamily N, polypeptide 13 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* /...ENSDARG0000004295349
cyp2p10 / cytochrome P450, family 2, subfamily P, polypeptide 10 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* /...ENSDARG0000004299049
cyp2j20 / cytochrome P450, family 2, subfamily J, polypeptide 20 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* /...ENSDARG0000009405749
cyp2v1 / cytochrome P450, family 2, subfamily V, polypeptide 1 / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54749* / O54750* / CYP2J2* / Cyp2j5* / Cyp2j11* / Cyp2j12* / Cyp2j13* / C...ENSDARG0000001848547
cyp2ae1 / cytochrome P450, family 2, subfamily AE, polypeptide 1 / CYP2J2* / O54749* / Cyp2j5* / Cyp2j6* / Cyp2j7* / Cyp2j8* / Cyp2j9* / P51589* / O54750* / Cyp2j13* / Cyp2j12* / Cyp2j11* /...ENSDARG0000001352445
FO904880.1 / CYP2J2* / P51589* / cytochrome P450 family 2 subfamily J member 2*ENSDARG0000011036644
F1Q8C3 / cyp2k6 / cytochrome P450, family 2, subfamily K, polypeptide 6 / Q8TAV3* / CYP2W1* / E9Q816* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000009899541
cyp2k6 / cyp2k31 / cytochrome P450, family 2, subfamily K, polypeptide 6 / E9Q816* / CYP2W1* / Q8TAV3* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000000987440
cyp2k22 / cytochrome P450, family 2, subfamily K, polypeptide 22 / Q8TAV3* / CYP2W1* / E9Q816* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000004043340
cyp2r1 / cytochrome P450, family 2, subfamily R, polypeptide 1 / Q6VVW9* / Q6VVX0* / Vitamin D 25-hydroxylase * / cytochrome P450 family 2 subfamily R member 1*ENSDARG0000005658740
cyp2k8 / cytochrome P450, family 2, subfamily K, polypeptide 8 / Q8TAV3* / CYP2W1* / E9Q816* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000010119040
cyp2k20 / cytochrome P450, family 2, subfamily k, polypeptide 20 / Q8TAV3* / CYP2W1* / E9Q816* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000010163240
cyp2k16 / cytochrome P450, family 2, subfamily K, polypeptide16 / Q8TAV3* / CYP2W1* / E9Q816* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000010298139
cyp2k20 / cyp2k21 / cytochrome P450, family 2, subfamily k, polypeptide 21 / E9Q816* / CYP2W1* / Q8TAV3* / Cytochrome P450 2W1 * / cytochrome P450 family 2 subfamily W member 1*ENSDARG0000010515139


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008069  Cytochrome P450, E-class, group I, CYP2D-like
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Fatty acids
Xenobiotics
Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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