ENSDARG00000023713


Danio rerio

Features
Gene ID: ENSDARG00000023713
  
Biological name :aqp1a.1
  
Synonyms : aqp1a.1 / aquaporin 1a (Colton blood group), tandem duplicate 1
  
Possible biological names infered from orthology : AC004691.2 / AQP1 / Aquaporin-1 / aquaporin 1 (Colton blood group) / P29972 / Q02013
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 2737422
Gene end: 2749333
  
Corresponding Affymetrix probe sets: Dr.22360.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000036702
NCBI entrez gene - 335821     See in Manteia.
swissprot - Q6NZ72
ZFIN ID - ZDB-GENE-030131-7764
Ensembl - ENSDARG00000023713
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AQP1ENSGALG00000005209Gallus gallus
 AC004691.2ENSG00000250424Homo sapiens
 AQP1ENSG00000240583Homo sapiens
 Aqp1ENSMUSG00000004655Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
aqp1a.2 / aquaporin 1a (Colton blood group), tandem duplicate 2 / AQP1* / P29972* / AC004691.2* / aquaporin 1 (Colton blood group)*ENSDARG0000009102764
aqp4 / aquaporin 4 / P55087* / aquaporin-4 isoform M1x *ENSDARG0000001056545
mipa / major intrinsic protein of lens fiber a / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*ENSDARG0000003728544
mipb / major intrinsic protein of lens fiber b / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*ENSDARG0000001396343
CR450824.2ENSDARG0000010392734
CT573446.1ENSDARG0000010500732
aqp8a.1 / aquaporin 8a, tandem duplicate 1 / AQP8* / O94778* / P56404* / aquaporin 8*ENSDARG0000004514125
aqp8a.2 / aquaporin 8a, tandem duplicate 2ENSDARG0000007159225
aqp8b / aquaporin 8bENSDARG0000008974921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000425  Major intrinsic protein
 IPR022357  Major intrinsic protein, conserved site
 IPR023271  Aquaporin-like
 IPR034294  Aquaporin transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006833 water transport IEA
 biological_processGO:0015670 carbon dioxide transport IMP
 biological_processGO:0015696 ammonium transport IMP
 biological_processGO:0035378 carbon dioxide transmembrane transport IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0072488 ammonium transmembrane transport IEA
 biological_processGO:0120029 proton export across plasma membrane IMP
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IBA
 molecular_functionGO:0005372 water transmembrane transporter activity IDA
 molecular_functionGO:0008519 ammonium transmembrane transporter activity IDA
 molecular_functionGO:0015250 water channel activity IDA
 molecular_functionGO:0015267 channel activity IEA
 molecular_functionGO:0035379 carbon dioxide transmembrane transporter activity IDA


Pathways (from Reactome)
Pathway description
Erythrocytes take up carbon dioxide and release oxygen
Erythrocytes take up oxygen and release carbon dioxide
Vasopressin regulates renal water homeostasis via Aquaporins
Passive transport by Aquaporins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure decreased amount , abnormal
Show

 ZFA:0000114 heart heart decreased amount , abnormal
Show

 ZFA:0000354 gill gill decreased amount , abnormal
Show

 ZFA:0000368 integument integument proton export across plasma membrane decreased process quality , abnormal
Show

 ZFA:0005086 pectoral artery pectoral artery decreased amount , abnormal
Show

 ZFA:0005323 ionocyte ionocyte proton export across plasma membrane decreased process quality , abnormal
Show

 ZFA:0005327 vH ionocyte vH ionocyte proton export across plasma membrane process quality , ameliorated
vH ionocyte proton export across plasma membrane decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000023713 aqp1a.1 / aquaporin 1a (Colton blood group), tandem duplicate 1 / AQP1* / P29972* / AC004691.2* / aquaporin 1 (Colton blood group)*  / complex






 

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