ENSDARG00000037285


Danio rerio

Features
Gene ID: ENSDARG00000037285
  
Biological name :mipa
  
Synonyms : major intrinsic protein of lens fiber a / mipa
  
Possible biological names infered from orthology : Lens fiber major intrinsic protein / major intrinsic protein of lens fiber / MIP / P30301 / P51180
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 27068225
Gene end: 27072774
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000054237
NCBI entrez gene - 445140     See in Manteia.
RefSeq - NM_001003534
RefSeq Peptide - NP_001003534
swissprot - Q6DEI6
ZFIN ID - ZDB-GENE-040801-41
Ensembl - ENSDARG00000037285
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MIPENSGALG00000042119Gallus gallus
 MIPENSG00000135517Homo sapiens
 MipENSMUSG00000025389Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
mipb / major intrinsic protein of lens fiber b / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*ENSDARG0000001396385
aqp1a.2 / aquaporin 1a (Colton blood group), tandem duplicate 2 / AQP1* / P29972* / AC004691.2* / aquaporin 1 (Colton blood group)*ENSDARG0000009102746
aqp4 / aquaporin 4 / P55087* / aquaporin-4 isoform M1x *ENSDARG0000001056543
aqp1a.1 / aquaporin 1a (Colton blood group), tandem duplicate 1 / AQP1* / P29972* / AC004691.2* / aquaporin 1 (Colton blood group)*ENSDARG0000002371343
CR450824.2ENSDARG0000010392729
CT573446.1ENSDARG0000010500729
aqp8a.1 / aquaporin 8a, tandem duplicate 1 / AQP8* / O94778* / P56404* / aquaporin 8*ENSDARG0000004514127
aqp8a.2 / aquaporin 8a, tandem duplicate 2ENSDARG0000007159227
aqp8b / aquaporin 8bENSDARG0000008974927


Protein motifs (from Interpro)
Interpro ID Name
 IPR000425  Major intrinsic protein
 IPR022357  Major intrinsic protein, conserved site
 IPR023271  Aquaporin-like
 IPR034294  Aquaporin transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0006833 water transport IDA
 biological_processGO:0034220 ion transmembrane transport IBA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IBA
 molecular_functionGO:0005372 water transmembrane transporter activity IDA
 molecular_functionGO:0015250 water channel activity IMP
 molecular_functionGO:0015267 channel activity IEA


Pathways (from Reactome)
Pathway description
Passive transport by Aquaporins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000035 lens lens rough , abnormal
lens opaque , abnormal
lens morphology , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000013963 mipb / major intrinsic protein of lens fiber b / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*  / complex
 ENSDARG00000037285 mipa / major intrinsic protein of lens fiber a / MIP* / P30301* / P51180* / Lens fiber major intrinsic protein * / major intrinsic protein of lens fiber*  / complex






 

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