ENSGALG00000042119


Gallus gallus

Features
Gene ID: ENSGALG00000042119
  
Biological name :MIP
  
Synonyms : Lens fiber major intrinsic protein / MIP / P28238
  
Possible biological names infered from orthology : major intrinsic protein of lens fiber / P30301 / P51180
  
Species: Gallus gallus
  
Chr. number: 33
Strand: -1
Band:
Gene start: 783896
Gene end: 785822
  
Corresponding Affymetrix probe sets: Gga.67.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000049696
Ensembl peptide - ENSGALP00000046011
NCBI entrez gene - 374124     See in Manteia.
RefSeq - NM_204266
RefSeq Peptide - NP_989597
swissprot - P28238
swissprot - A0A1D5P037
Ensembl - ENSGALG00000042119
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 mipaENSDARG00000037285Danio rerio
 mipbENSDARG00000013963Danio rerio
 MIPENSG00000135517Homo sapiens
 MipENSMUSG00000025389Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AQP2 / aquaporin-2 / P41181* / P56402*ENSGALG0000003787850
AQP5 / aquaporin 5 / P55064* / Q9WTY4*ENSGALG0000004187850
AQP4 / aquaporin-4 isoform 1 / P55087* / aquaporin 4* / aquaporin-4 isoform M1x *ENSGALG0000001512843
AQP1 / Q02013* / P29972* / AC004691.2* / Aquaporin-1 * / aquaporin 1 (Colton blood group)*ENSGALG0000000520942


Protein motifs (from Interpro)
Interpro ID Name
 IPR000425  Major intrinsic protein
 IPR022357  Major intrinsic protein, conserved site
 IPR023254  Aquaporin 6
 IPR023271  Aquaporin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0006833 water transport IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0034220 ion transmembrane transport IBA
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 biological_processGO:0051289 protein homotetramerization IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1990349 gap junction-mediated intercellular transport IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane ISS
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0005921 gap junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IBA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005212 structural constituent of eye lens IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015250 water channel activity IEA
 molecular_functionGO:0015267 channel activity IEA


Pathways (from Reactome)
Pathway description
Passive transport by Aquaporins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000042119 MIP / P28238 / Lens fiber major intrinsic protein / P30301* / P51180* / major intrinsic protein of lens fiber*  / complex






 

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