ENSDARG00000025375


Danio rerio

Features
Gene ID: ENSDARG00000025375
  
Biological name :idh1
  
Synonyms : idh1 / isocitrate dehydrogenase 1 (NADP+), soluble
  
Possible biological names infered from orthology : isocitrate dehydrogenase (NADP(+)) 1, cytosolic / Isocitrate dehydrogenase [NADP] cytoplasmic / O75874 / O88844
  
Species: Danio rerio
  
Chr. number: 9
Strand: 1
Band:
Gene start: 28103735
Gene end: 28129476
  
Corresponding Affymetrix probe sets: Dr.25191.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000023774
Ensembl peptide - ENSDARP00000092112
swissprot - B0UXL2
swissprot - F6NIA7
ZFIN ID - ZDB-GENE-031006-1
Ensembl - ENSDARG00000025375
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IDH1ENSGALG00000008818Gallus gallus
 IDH1ENSG00000138413Homo sapiens
 Idh1ENSMUSG00000025950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
idh2 / isocitrate dehydrogenase 2 (NADP+), mitochondrial / P48735* / isocitrate dehydrogenase (NADP(+)) 2, mitochondrial*ENSDARG0000000379535


Protein motifs (from Interpro)
Interpro ID Name
 IPR004790  Isocitrate dehydrogenase NADP-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006102 isocitrate metabolic process IEA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004450 isocitrate dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
NADPH regeneration
Neutrophil degranulation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0001094 whole organism whole organism has extra parts of type common myeloid progenitor , abnormal
whole organism has fewer parts of type macrophage , abnormal
whole organism has fewer parts of type neutrophil , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000025375 idh1 / isocitrate dehydrogenase 1 (NADP+), soluble / O75874* / isocitrate dehydrogenase (NADP(+)) 1, cytosolic*  / complex






 

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