ENSGALG00000008818


Gallus gallus

Features
Gene ID: ENSGALG00000008818
  
Biological name :IDH1
  
Synonyms : IDH1 / isocitrate dehydrogenase (NADP(+)) 1, cytosolic
  
Possible biological names infered from orthology : Isocitrate dehydrogenase [NADP] cytoplasmic / O75874 / O88844
  
Species: Gallus gallus
  
Chr. number: 7
Strand: -1
Band:
Gene start: 13851496
Gene end: 13864094
  
Corresponding Affymetrix probe sets: GgaAffx.5541.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000045961
Ensembl peptide - ENSGALP00000063653
Ensembl peptide - ENSGALP00000063650
Ensembl peptide - ENSGALP00000048298
Ensembl peptide - ENSGALP00000014317
NCBI entrez gene - 424112     See in Manteia.
RefSeq - XM_421965
RefSeq - XM_004942682
RefSeq - XM_015289549
RefSeq - XM_015289550
swissprot - A0A1L1RXS9
swissprot - A0A1L1RXS5
swissprot - A0A1D5P6H1
swissprot - F1NPG2
Ensembl - ENSGALG00000008818
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 idh1ENSDARG00000025375Danio rerio
 IDH1ENSG00000138413Homo sapiens
 Idh1ENSMUSG00000025950Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IDH2 / isocitrate dehydrogenase / P54071* / P48735* / Isocitrate dehydrogenase [NADP], mitochondrial * / isocitrate dehydrogenase (NADP(+)) 2, mitochondrial*ENSGALG0000003443469


Protein motifs (from Interpro)
Interpro ID Name
 IPR004790  Isocitrate dehydrogenase NADP-dependent
 IPR019818  Isocitrate/isopropylmalate dehydrogenase, conserved site
 IPR024084  Isopropylmalate dehydrogenase-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006099 tricarboxylic acid cycle IEA
 biological_processGO:0006102 isocitrate metabolic process IEA
 biological_processGO:0006103 2-oxoglutarate metabolic process IEA
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0060696 regulation of phospholipid catabolic process IEA
 biological_processGO:0071071 regulation of phospholipid biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004448 isocitrate dehydrogenase activity IEA
 molecular_functionGO:0004450 isocitrate dehydrogenase (NADP+) activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051287 NAD binding IEA


Pathways (from Reactome)
Pathway description
NADPH regeneration
Neutrophil degranulation
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008818 IDH1 / isocitrate dehydrogenase (NADP(+)) 1, cytosolic / O75874* / O88844* / Isocitrate dehydrogenase [NADP] cytoplasmic *  / complex






 

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