ENSDARG00000025567


Danio rerio

Features
Gene ID: ENSDARG00000025567
  
Biological name :nf2b
  
Synonyms : neurofibromin 2b (merlin) / nf2b
  
Possible biological names infered from orthology :
  
Species: Danio rerio
  
Chr. number: 21
Strand: 1
Band:
Gene start: 25801345
Gene end: 25819707
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000112172
Ensembl peptide - ENSDARP00000113200
Ensembl peptide - ENSDARP00000035057
NCBI entrez gene - 405887     See in Manteia.
RefSeq - NM_212951
RefSeq Peptide - NP_998116
swissprot - E9QGK2
swissprot - Q6Q413
ZFIN ID - ZDB-GENE-040622-3
Ensembl - ENSDARG00000025567
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000002367Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nf2a / neurofibromin 2a (merlin) / NF2* / P35240* / P46662* / Merlin * / neurofibromin 2*ENSDARG0000002020469
ezrb / sytl3 / synaptotagmin-like 3 / EZR* / ezrin* / P15311* / P26040*ENSDARG0000002509142
msna / moesin a / MSN* / moesin* / P26038* / P26041*ENSDARG0000005812841
ezra / ezrin a / EZR* / ezrin* / P15311* / P26040*ENSDARG0000002094440
msnb / moesin b / MSN* / moesin* / P26038* / P26041*ENSDARG0000002874039
farp2 / FERM, RhoGEF and pleckstrin domain protein 2 / O94887* / Q91VS8* / FERM, ARH/RhoGEF and pleckstrin domain protein 2* / FERM, ARHGEF and pleckstrin domain-containing protein 2 *ENSDARG0000001642921
farp1 / FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) / Q9Y4F1* / F8VPU2* / FERM, ARH/RhoGEF and pleckstrin domain protein 1* / FERM, ARHGEF and pleckstrin dom...ENSDARG0000007438121
mylipa / Q6TEM9 / myosin regulatory light chain interacting protein a / MYLIP* / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP * / myosin regulatory light chain interacting protein*ENSDARG0000000885914
frmd7 / FERM domain containing 7 / A2AD83* / Q6ZUT3* / FERM domain-containing protein 7 *ENSDARG0000006895814
mylipb / myosin regulatory light chain interacting protein b / MYLIP* / Q8BM54* / Q8WY64* / E3 ubiquitin-protein ligase MYLIP * / myosin regulatory light chain interacting protein*ENSDARG0000005511813
si:ch211-243g6.3 / FRMD7* / A2AD83* / Q6ZUT3* / FERM domain containing 7* / FERM domain-containing protein 7 *ENSDARG0000007049513
CABZ01066921.1ENSDARG0000011205611


Protein motifs (from Interpro)
Interpro ID Name
 IPR000299  FERM domain
 IPR000798  Ezrin/radixin/moesin-like
 IPR008954  Moesin tail domain superfamily
 IPR011174  Ezrin/radixin/moesin
 IPR011259  Ezrin/radixin/moesin, C-terminal
 IPR011993  PH-like domain superfamily
 IPR014352  FERM/acyl-CoA-binding protein superfamily
 IPR018979  FERM, N-terminal
 IPR018980  FERM, C-terminal PH-like domain
 IPR019747  FERM conserved site
 IPR019748  FERM central domain
 IPR019749  Band 4.1 domain
 IPR029071  Ubiquitin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000109 forebrain forebrain decreased size , abnormal
Show

 ZFA:0000112 gut gut quality , abnormal
gut hypoplastic , abnormal
Show

 ZFA:0000123 liver liver increased size , abnormal
liver quality , abnormal
Show

 ZFA:0000208 gall bladder gall bladder dilated , abnormal
gall bladder quality , abnormal
Show

 ZFA:0001094 whole organism whole organism shape , abnormal
whole organism bent , abnormal
Show

 ZFA:0001114 head head decreased width , abnormal
Show

 ZFA:0001115 trunk trunk bent , abnormal
Show

 ZFA:0001439 anatomical system anatomical system quality , abnormal
Show

 ZFA:0005165 common bile duct common bile duct morphology , abnormal
common bile duct dilated , abnormal
common bile duct cystic , abnormal
Show

 ZFA:0009111 hepatocyte hepatocyte increased distance hepatocyte , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr