ENSDARG00000030687


Danio rerio

Features
Gene ID: ENSDARG00000030687
  
Biological name :phka2
  
Synonyms : phka2 / phosphorylase kinase, alpha 2 (liver)
  
Possible biological names infered from orthology : P46019 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / phosphorylase kinase regulatory subunit alpha 2 / Q8BWJ3
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 33870357
Gene end: 33919309
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072664
Ensembl peptide - ENSDARP00000153291
NCBI entrez gene - 556199     See in Manteia.
swissprot - F1R3D9
ZFIN ID - ZDB-GENE-130422-1
Ensembl - ENSDARG00000030687
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PHKA2ENSGALG00000016518Gallus gallus
 PHKA2ENSG00000044446Homo sapiens
 Phka2ENSMUSG00000031295Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hdac8 / histone deacetylase 8ENSDARG0000010515964
phka1b / phosphorylase kinase, alpha 1b (muscle)ENSDARG0000010503961
phkb / phosphorylase kinase, beta / Q7TSH2* / Q93100* / phosphorylase kinase regulatory subunit beta* / Phosphorylase b kinase regulatory subunit beta *ENSDARG0000007828432


Protein motifs (from Interpro)
Interpro ID Name
 IPR008734  Phosphorylase kinase alpha/beta subunit
 IPR008928  Six-hairpin glycosidase superfamily
 IPR011613  GH15-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005964 phosphorylase kinase complex IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004689 phosphorylase kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IEA


Pathways (from Reactome)
Pathway description
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000002197 pygl / phosphorylase, glycogen, liver / P06737* / Q9ET01* / glycogen phosphorylase L* / Glycogen phosphorylase, liver form *  / reaction
 ENSDARG00000054208 phkg2 / phosphorylase kinase, gamma 2 (testis) / Q9DB30* / P15735* / phosphorylase kinase catalytic subunit gamma 2* / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform *  / complex
 ENSDARG00000030687 phka2 / phosphorylase kinase, alpha 2 (liver) / Q8BWJ3* / P46019* / phosphorylase kinase regulatory subunit alpha 2* / Phosphorylase b kinase regulatory subunit alpha, liver isoform *  / complex
 ENSDARG00000100825 calm2a / calm2b / calm3a / Q6PI52 / calmodulin 2a (phosphorylase kinase, delta)  / complex
 ENSDARG00000078284 phkb / phosphorylase kinase, beta / Q7TSH2* / Q93100* / phosphorylase kinase regulatory subunit beta* / Phosphorylase b kinase regulatory subunit beta *  / complex






 

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