ENSMUSG00000031295


Mus musculus

Features
Gene ID: ENSMUSG00000031295
  
Biological name :Phka2
  
Synonyms : Phka2 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / Q8BWJ3
  
Possible biological names infered from orthology : P46019 / phosphorylase kinase regulatory subunit alpha 2
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: F4
Gene start: 160502166
Gene end: 160598878
  
Corresponding Affymetrix probe sets: 10602925 (MoGene1.0st)   1430492_at (Mouse Genome 430 2.0 Array)   1434518_at (Mouse Genome 430 2.0 Array)   1437941_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000033652
Ensembl peptide - ENSMUSP00000107996
Ensembl peptide - ENSMUSP00000107999
Ensembl peptide - ENSMUSP00000118575
Ensembl peptide - ENSMUSP00000107995
NCBI entrez gene - 110094     See in Manteia.
MGI - MGI:97577
RefSeq - XM_006528682
RefSeq - NM_001177878
RefSeq - NM_001177879
RefSeq - NM_172783
RefSeq - XM_006528679
RefSeq - XM_006528680
RefSeq - XM_006528681
RefSeq Peptide - NP_766371
RefSeq Peptide - NP_001171349
RefSeq Peptide - NP_001171350
swissprot - A2AHQ7
swissprot - Q8BWJ3
swissprot - A2AHQ8
swissprot - Q6PE66
Ensembl - ENSMUSG00000031295
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phka2ENSDARG00000030687Danio rerio
 PHKA2ENSGALG00000016518Gallus gallus
 PHKA2ENSG00000044446Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phka1 / P18826 / Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform / P46020* / phosphorylase kinase regulatory subunit alpha 1*ENSMUSG0000003405568
Phkb / Q7TSH2 / Phosphorylase b kinase regulatory subunit beta / Q93100* / phosphorylase kinase regulatory subunit beta*ENSMUSG0000003687931


Protein motifs (from Interpro)
Interpro ID Name
 IPR008734  Phosphorylase kinase alpha/beta subunit
 IPR008928  Six-hairpin glycosidase superfamily
 IPR011613  GH15-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005964 phosphorylase kinase complex IBA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004689 phosphorylase kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IEA


Pathways (from Reactome)
Pathway description
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / complex
 ENSMUSG00000030815 Phkg2 / Q9DB30 / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform / P15735* / phosphorylase kinase catalytic subunit gamma 2*  / complex
 ENSMUSG00000031295 Phka2 / Q8BWJ3 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / P46019* / phosphorylase kinase regulatory subunit alpha 2*  / complex
 ENSMUSG00000036879 Phkb / Q7TSH2 / Phosphorylase b kinase regulatory subunit beta / Q93100* / phosphorylase kinase regulatory subunit beta*  / complex
 ENSMUSG00000021069 Pygl / Q9ET01 / Glycogen phosphorylase, liver form / P06737* / glycogen phosphorylase L*  / reaction






 

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