ENSDARG00000031020


Danio rerio
-phosphate-kinasepip4k2caactivitypiphosphorylationbindingkinasesynthesispipspcorec-terminaln-terminalmetabolicprocessnucleotideatpphosphatetransferaseplasmamembraneregulatestpacetylationppierregulatek

Features
Gene ID: ENSDARG00000031020
  
Biological name :pip4k2ca
  
Synonyms : phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a / pip4k2ca
  
Possible biological names infered from orthology : phosphatidylinositol-5-phosphate 4-kinase type 2 gamma / PIP4K2C / Q8TBX8 / Q91XU3
  
Species: Danio rerio
  
Chr. number: 23
Strand: 1
Band:
Gene start: 36616717
Gene end: 36645135
  
Corresponding Affymetrix probe sets: Dr.21910.1.A1_at (Zebrafish Array)   Dr.4621.1.S1_at (Zebrafish Array)   NM_200101_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000042700
Ensembl peptide - ENSDARP00000157397
NCBI entrez gene - 373124     See in Manteia.
RefSeq - NM_200101
RefSeq Peptide - NP_956395
swissprot - F1REU6
ZFIN ID - ZDB-GENE-030828-9
Ensembl - ENSDARG00000031020
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q8TBX8ENSG00000166908Homo sapiens
 Q91XU3ENSMUSG00000025417Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pip4k2cb / phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b / Q8TBX8* / PIP4K2C* / phosphatidylinositol-5-phosphate 4-kinase type 2 gamma*ENSDARG0000009163777
pip4k2ab / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*ENSDARG0000006354463
pip4k2aa / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*ENSDARG0000000377662
pip5k1ab / phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b / P70182* / Q99755* / PIP5K1A* / phosphatidylinositol-4-phosphate 5-kinase type 1 alpha*ENSDARG0000002464229
pip5k1cb / phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b / O60331* / O70161* / PIP5K1C* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSDARG0000010031329
pip5k1aa / phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a / P70182* / Q99755* / PIP5K1A* / phosphatidylinositol-4-phosphate 5-kinase type 1 alpha*ENSDARG0000010039629
pip5k1ba / phosphatidylinositol-4-phosphate 5-kinase, type I, beta a / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000004429528
pip5k1ca / phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a / O60331* / O70161* / PIP5K1C* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSDARG0000007600128
pip5k1bb / phosphatidylinositol-4-phosphate 5-kinase, type I, beta b / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000000650827
pip5kl1 / phosphatidylinositol-4-phosphate 5-kinase-like 1 / Q5T9C9* / Q6U7H8* / Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 *ENSDARG0000006094620
si:dkey-3h23.3 / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG000001048497


Protein motifs (from Interpro)
Interpro ID Name
 IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
 IPR023610  Phosphatidylinositol-4-phosphate 5-kinase
 IPR027483  Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
 IPR027484  Phosphatidylinositol-4-phosphate 5-kinase, N-terminal


Gene Ontology (GO)
cellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcellular metabolic processcellular metabolic processprimary metabolic processprimary metabolic processorganic substance metabolic processorganic substance metabolic process
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingion bindingcarbohydrate derivative bindingdrug bindingtransferase activityorganic cyclic compoorganic cyclic compound bindingheterocyclic compounheterocyclic compound bindingsmall molecule bindismall molecule bindingion bindingion bindingcarbohydrate derivatcarbohydrate derivative bindingdrug bindingdrug bindingtransferase activitytransferase activity
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
PI5P Regulates TP53 Acetylation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Synthesis of PIPs in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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