ENSDARG00000063544


Danio rerio

Features
Gene ID: ENSDARG00000063544
  
Biological name :pip4k2ab
  
Synonyms : phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b / pip4k2ab
  
Possible biological names infered from orthology : O70172 / P48426 / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha / PIP4K2A
  
Species: Danio rerio
  
Chr. number: 2
Strand: 1
Band:
Gene start: 21090317
Gene end: 21156855
  
Corresponding Affymetrix probe sets: Dr.14125.1.A1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113001
Ensembl peptide - ENSDARP00000122520
Ensembl peptide - ENSDARP00000102384
NCBI entrez gene - 555920     See in Manteia.
swissprot - B0UXW0
swissprot - F1QIQ0
swissprot - F1QWU0
ZFIN ID - ZDB-GENE-070912-272
Ensembl - ENSDARG00000063544
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PIP4K2AENSGALG00000007877Gallus gallus
 P48426ENSG00000150867Homo sapiens
 O70172ENSMUSG00000026737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
pip4k2aa / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*ENSDARG0000000377685
pip4k2ca / phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a / Q8TBX8* / PIP4K2C* / phosphatidylinositol-5-phosphate 4-kinase type 2 gamma*ENSDARG0000003102063
pip4k2cb / phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b / Q8TBX8* / PIP4K2C* / phosphatidylinositol-5-phosphate 4-kinase type 2 gamma*ENSDARG0000009163760
pip5k1cb / phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b / O60331* / O70161* / PIP5K1C* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSDARG0000010031330
pip5k1ab / phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b / P70182* / Q99755* / PIP5K1A* / phosphatidylinositol-4-phosphate 5-kinase type 1 alpha*ENSDARG0000002464229
pip5k1ca / phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a / O60331* / O70161* / PIP5K1C* / phosphatidylinositol-4-phosphate 5-kinase type 1 gamma*ENSDARG0000007600128
pip5k1aa / phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a / P70182* / Q99755* / PIP5K1A* / phosphatidylinositol-4-phosphate 5-kinase type 1 alpha*ENSDARG0000010039628
pip5k1bb / phosphatidylinositol-4-phosphate 5-kinase, type I, beta b / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000000650826
pip5k1ba / phosphatidylinositol-4-phosphate 5-kinase, type I, beta a / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG0000004429526
pip5kl1 / phosphatidylinositol-4-phosphate 5-kinase-like 1 / Q5T9C9* / Q6U7H8* / Phosphatidylinositol 4-phosphate 5-kinase-like protein 1 *ENSDARG0000006094622
si:dkey-3h23.3 / O14986* / P70181* / PIP5K1B* / phosphatidylinositol-4-phosphate 5-kinase type 1 beta*ENSDARG000001048498


Protein motifs (from Interpro)
Interpro ID Name
 IPR002498  Phosphatidylinositol-4-phosphate 5-kinase, core
 IPR023610  Phosphatidylinositol-4-phosphate 5-kinase
 IPR027483  Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
 IPR027484  Phosphatidylinositol-4-phosphate 5-kinase, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046488 phosphatidylinositol metabolic process IEA
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016307 phosphatidylinositol phosphate kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of PIPs at the plasma membrane
PI5P Regulates TP53 Acetylation
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Synthesis of PIPs in the nucleus


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000003776 pip4k2aa / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha a / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*  / complex
 ENSDARG00000063544 pip4k2ab / phosphatidylinositol-5-phosphate 4-kinase, type II, alpha b / O70172* / P48426* / PIP4K2A* / phosphatidylinositol-5-phosphate 4-kinase type 2 alpha*  / complex
 ENSDARG00000091637 pip4k2cb / phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b / Q8TBX8* / PIP4K2C* / phosphatidylinositol-5-phosphate 4-kinase type 2 gamma*  / complex






 

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