ENSDARG00000031702


Danio rerio

Features
Gene ID: ENSDARG00000031702
  
Biological name :prkg1b
  
Synonyms : prkg1b / protein kinase, cGMP-dependent, type Ib
  
Possible biological names infered from orthology : P0C605 / PRKG1 / protein kinase, cGMP-dependent, type I / Q13976
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 6195191
Gene end: 6451609
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000149592
Ensembl peptide - ENSDARP00000043235
Ensembl peptide - ENSDARP00000126641
Ensembl peptide - ENSDARP00000146350
NCBI entrez gene - 566430     See in Manteia.
swissprot - F1R125
swissprot - R4GDT5
ZFIN ID - ZDB-GENE-080225-40
Ensembl - ENSDARG00000031702
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PRKG1ENSGALG00000003805Gallus gallus
 PRKG1ENSG00000185532Homo sapiens
 Prkg1ENSMUSG00000052920Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
prkg1a / protein kinase, cGMP-dependent, type IaENSDARG0000002065683
prkg2 / protein kinase, cGMP-dependent, type II / Q13237*ENSDARG0000005474150
si:dkey-121j17.5ENSDARG0000001423240
prkacba / protein kinase, cAMP-dependent, catalytic, beta aENSDARG0000000178222
prkx / protein kinase, X-linked / P51817* / Q922R0* / cAMP-dependent protein kinase catalytic subunit PRKX *ENSDARG0000006071622
prkacaa / protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate aENSDARG0000010034922
prkacab / protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate bENSDARG0000001680921
prkacbb / protein kinase, cAMP-dependent, catalytic, beta b / P22694* / PRKACB* / protein kinase cAMP-activated catalytic subunit beta*ENSDARG0000005912521


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR000719  Protein kinase domain
 IPR000961  AGC-kinase, C-terminal
 IPR002374  cGMP-dependent kinase
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR014710  RmlC-like jelly roll fold
 IPR017441  Protein kinase, ATP binding site
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like
 IPR031831  cGMP-dependent protein kinase, N-terminal coiled-coil domain
 IPR035014  cGMP-dependent protein kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004692 cGMP-dependent protein kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030553 cGMP binding IEA


Pathways (from Reactome)
Pathway description
Rap1 signalling
cGMP effects


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000014655 itpr1a / inositol 1,4,5-trisphosphate receptor, type 1a / ITPR1* / P11881* / Q14643* / inositol 1,4,5-trisphosphate receptor type 1*  / reaction
 ENSDARG00000061551 rap1gap2a / RAP1 GTPase activating protein 2a / Q5SVL6* / Q684P5* / RAP1GAP2* / RAP1 GTPase activating protein 2*  / reaction
 ENSDARG00000074602 mrvi1 / murine retrovirus integration site 1 homolog / Q9WUX5* / Q9Y6F6* / Protein MRVI1 *  / reaction






 

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