ENSDARG00000034368


Danio rerio

Features
Gene ID: ENSDARG00000034368
  
Biological name :hexb
  
Synonyms : hexb / hexosaminidase B (beta polypeptide)
  
Possible biological names infered from orthology : Beta-hexosaminidase subunit beta / hexosaminidase subunit beta / P07686 / P20060
  
Species: Danio rerio
  
Chr. number: 5
Strand: -1
Band:
Gene start: 34600714
Gene end: 34616599
  
Corresponding Affymetrix probe sets: Dr.18068.1.A1_at (Zebrafish Array)   Dr.5384.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000113789
Ensembl peptide - ENSDARP00000050270
Ensembl peptide - ENSDARP00000088748
NCBI entrez gene - 323613     See in Manteia.
RefSeq - NM_001309863
RefSeq - XM_009301448
RefSeq Peptide - NP_001296792
RefSeq Peptide - NP_001108317
swissprot - F1QUU0
swissprot - A2BHD8
swissprot - F1QTE2
ZFIN ID - ZDB-GENE-030131-2333
Ensembl - ENSDARG00000034368
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HEXBENSGALG00000014933Gallus gallus
 HEXBENSG00000049860Homo sapiens
 HexbENSMUSG00000021665Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hexa / hexosaminidase A (alpha polypeptide) / P29416* / P06865* / AC009690.1* / hexosaminidase subunit alpha* / Beta-hexosaminidase subunit alpha *ENSDARG0000005211355


Protein motifs (from Interpro)
Interpro ID Name
 IPR015883  Glycoside hydrolase family 20, catalytic domain
 IPR017853  Glycoside hydrolase superfamily
 IPR025705  Beta-hexosaminidase
 IPR029018  Beta-hexosaminidase-like, domain 2
 IPR029019  Beta-hexosaminidase, eukaryotic type, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0008152 metabolic process IEA
 molecular_functionGO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds IEA
 molecular_functionGO:0004563 beta-N-acetylhexosaminidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016798 hydrolase activity, acting on glycosyl bonds IEA
 molecular_functionGO:0102148 N-acetyl-beta-D-galactosaminidase activity IEA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism
Keratan sulfate degradation
CS/DS degradation
Hyaluronan uptake and degradation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000084 yolk yolk edematous , abnormal
Show

 ZFA:0000106 extension extension distended , abnormal
Show

 ZFA:0001079 blood vasculature blood vasculature broken , abnormal
Show

 ZFA:0001094 whole organism whole organism curved ventral , abnormal
Show

 ZFA:0001114 head head decreased size , abnormal
Show

 ZFA:0001285 intersegmental vessel intersegmental vessel morphology , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052113 hexa / hexosaminidase A (alpha polypeptide) / P29416* / P06865* / AC009690.1* / hexosaminidase subunit alpha* / Beta-hexosaminidase subunit alpha *  / complex
 ENSDARG00000034368 hexb / hexosaminidase B (beta polypeptide) / P07686* / P20060* / hexosaminidase subunit beta* / Beta-hexosaminidase subunit beta *  / complex
 ENSDARG00000088439 gm2a / GM2 ganglioside activator / P17900*  / reaction
 ENSDARG00000107431 LO018208.1 / GM2A* / P17900* / GM2 ganglioside activator*  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr