ENSDARG00000034624


Danio rerio

Features
Gene ID: ENSDARG00000034624
  
Biological name :nuf2
  
Synonyms : nuf2 / NUF2, NDC80 kinetochore complex component, homolog / Q7ZW63
  
Possible biological names infered from orthology : Mus musculus NUF2, NDC80 kinetochore complex component (Nuf2), transcript variant 2, mRNA. / NUF2, NDC80 kinetochore complex component / Q99P69 / Q9BZD4
  
Species: Danio rerio
  
Chr. number: 11
Strand: -1
Band:
Gene start: 429776
Gene end: 438518
  
Corresponding Affymetrix probe sets: Dr.15726.1.S1_at (Zebrafish Array)   NM_200310_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000040811
Ensembl peptide - ENSDARP00000119923
Ensembl peptide - ENSDARP00000114276
NCBI entrez gene - 393280     See in Manteia.
RefSeq - NM_200310
RefSeq - XM_005155671
RefSeq Peptide - NP_956604
swissprot - E9QD03
swissprot - Q7ZW63
swissprot - E9QBK4
ZFIN ID - ZDB-GENE-040426-1121
Ensembl - ENSDARG00000034624
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NUF2ENSGALG00000003438Gallus gallus
 NUF2ENSG00000143228Homo sapiens
 Nuf2ENSMUSG00000026683Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR005549  Kinetochore protein Nuf2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0031262 Ndc80 complex IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000012 central nervous system central nervous system necrotic , abnormal
Show

 ZFA:0000396 nervous system nervous system quality , abnormal
Show

 ZFA:0001094 whole organism whole organism viability , abnormal
whole organism necrotic , abnormal
whole organism atrophied , abnormal
Show

 ZFA:0001114 head head flat , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000071694 ndc80 / Q6DRJ7 / NDC80 kinetochore complex component / O14777* / Q9D0F1* / Kinetochore *  / complex
 ENSDARG00000024471 nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSDARG00000077822 si:dkey-6i22.5 / PMF1* / Q6P1K2* / Q9CPV5* / PMF1-BGLAP* / PMF1-BGLAP readthrough* / polyamine modulated factor 1*  / complex
 ENSDARG00000089922 dsn1 / DSN1 homolog, MIS12 kinetochore complex component / Q9H410*  / complex
 ENSDARG00000093622 spc24 / Q503N2 / SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9D083* / Q8NBT2* / Kinetochore protein Spc24 * / SPC24, NDC80 kinetochore complex component*  / complex
 ENSDARG00000078433 spc25 / SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9HBM1* / Q3UA16* / Kinetochore protein Spc25 * / SPC25, NDC80 kinetochore complex component*  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr