ENSDARG00000093622


Danio rerio

Features
Gene ID: ENSDARG00000093622
  
Biological name :spc24
  
Synonyms : Q503N2 / spc24 / SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
  
Possible biological names infered from orthology : Kinetochore protein Spc24 / Q8NBT2 / Q9D083 / SPC24, NDC80 kinetochore complex component
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 19355869
Gene end: 19363981
  
Corresponding Affymetrix probe sets: Dr.15855.1.A1_at (Zebrafish Array)   NM_001024440_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000059307
NCBI entrez gene - 554147     See in Manteia.
RefSeq - NM_001024440
RefSeq Peptide - NP_001019611
swissprot - A7MCQ0
swissprot - Q503N2
ZFIN ID - ZDB-GENE-050522-456
Ensembl - ENSDARG00000093622
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPC24ENSG00000161888Homo sapiens
 Spc24ENSMUSG00000074476Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013252  Kinetochore-Ndc80 subunit Spc24


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0031262 Ndc80 complex ISS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000071694 ndc80 / Q6DRJ7 / NDC80 kinetochore complex component / O14777* / Q9D0F1* / Kinetochore *  / complex
 ENSDARG00000024471 nsl1 / NSL1, MIS12 kinetochore complex component / Q96IY1*  / complex
 ENSDARG00000034624 nuf2 / Q7ZW63 / NUF2, NDC80 kinetochore complex component, homolog / Q99P69* / Q9BZD4* / NUF2, NDC80 kinetochore complex component* / Mus musculus NUF2, NDC80 kinetochore complex component ...  / complex
 ENSDARG00000077822 si:dkey-6i22.5 / PMF1* / Q6P1K2* / Q9CPV5* / PMF1-BGLAP* / PMF1-BGLAP readthrough* / polyamine modulated factor 1*  / complex
 ENSDARG00000078433 spc25 / SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) / Q9HBM1* / Q3UA16* / Kinetochore protein Spc25 * / SPC25, NDC80 kinetochore complex component*  / complex
 ENSDARG00000089922 dsn1 / DSN1 homolog, MIS12 kinetochore complex component / Q9H410*  / complex






 

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