ENSDARG00000037879


Danio rerio

Features
Gene ID: ENSDARG00000037879
  
Biological name :lfng
  
Synonyms : lfng / LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase / Q8JHF2
  
Possible biological names infered from orthology : Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe / O09010 / Q8NES3
  
Species: Danio rerio
  
Chr. number: 3
Strand: 1
Band:
Gene start: 41917499
Gene end: 41926869
  
Corresponding Affymetrix probe sets: Dr.1831.1.S1_at (Zebrafish Array)   NM_130971_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000031031
Ensembl peptide - ENSDARP00000115632
NCBI entrez gene - 30158     See in Manteia.
RefSeq - NM_130971
RefSeq Peptide - NP_571046
swissprot - F1Q7Y0
swissprot - B2GQK5
swissprot - Q8JHF2
ZFIN ID - ZDB-GENE-980605-16
Ensembl - ENSDARG00000037879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LFNGENSGALG00000038515Gallus gallus
 LFNGENSG00000106003Homo sapiens
 LfngENSMUSG00000029570Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
rfng / RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase / O09009* / Q9Y644* / Beta-1,3-N-acetylglucosaminyltransferase radical fringe *ENSDARG0000001974651
mfng / Q5YB40 / MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase / O00587* / O09008* / Beta-1,3-N-acetylglucosaminyltransferase manic fringe *ENSDARG0000004292545


Protein motifs (from Interpro)
Interpro ID Name
 IPR003378  Fringe-like
 IPR017374  Fringe


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007389 pattern specification process IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0008593 regulation of Notch signaling pathway ISS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031101 fin regeneration IMP
 biological_processGO:0036066 protein O-linked fucosylation ISS
 biological_processGO:0045665 negative regulation of neuron differentiation IMP
 biological_processGO:0055016 hypochord development IMP
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030173 integral component of Golgi membrane IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000029 hindbrain hindbrain interneuron increased amount , abnormal
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 ZFA:0000206 facial nerve motor nucleus facial nerve motor nucleus increased amount , abnormal
Show

 ZFA:0000297 vagal lobe vagal lobe increased amount , abnormal
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 ZFA:0001365 trigeminal motor nucleus trigeminal motor nucleus increased amount , abnormal
Show

 ZFA:0005177 VeLD VeLD increased amount , abnormal
Show

 ZFA:0005233 CiD CiD increased amount , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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