ENSDARG00000038967


Danio rerio

Features
Gene ID: ENSDARG00000038967
  
Biological name :cul3a
  
Synonyms : cul3a / cullin 3a
  
Possible biological names infered from orthology : CUL3 / cullin 3 / Q13618 / Q9JLV5
  
Species: Danio rerio
  
Chr. number: 2
Strand: -1
Band:
Gene start: 47644041
Gene end: 47681454
  
Corresponding Affymetrix probe sets: Dr.2145.1.A1_at (Zebrafish Array)   NM_199691_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000056881
NCBI entrez gene - 324655     See in Manteia.
RefSeq - NM_199691
RefSeq Peptide - NP_955985
swissprot - F6NVK8
ZFIN ID - ZDB-GENE-030131-3376
Ensembl - ENSDARG00000038967
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CUL3ENSGALG00000005108Gallus gallus
 CUL3ENSG00000036257Homo sapiens
 Cul3ENSMUSG00000004364Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cul3b / cullin 3b / CUL3* / Q13618* / Q9JLV5* / cullin 3*ENSDARG0000010010896
cul4b / cullin 4B / A2A432* / Q13620*ENSDARG0000006051037
cul4a / cullin 4A / Q13619* / Q3TCH7*ENSDARG0000009657831
cul1b / cullin 1b / CUL1* / Q13616* / Q9WTX6* / cullin 1* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*ENSDARG0000000769130
cul1a / cullin 1a / CUL1* / Q13616* / Q9WTX6* / cullin 1* / Mus musculus cullin 1 (Cul1), transcript variant 3, mRNA.*ENSDARG0000001923930
cul2 / cullin 2 / Q13617* / Q9D4H8*ENSDARG0000001396527
cul5b / cullin 5b / CUL5* / Q93034* / cullin 5*ENSDARG0000000426023
cul5a / cullin 5a / CUL5* / Q93034* / cullin 5*ENSDARG0000006974223


Protein motifs (from Interpro)
Interpro ID Name
 IPR001373  Cullin, N-terminal
 IPR011991  ArsR-like helix-turn-helix domain
 IPR016157  Cullin, conserved site
 IPR016158  Cullin homology domain
 IPR016159  Cullin repeat-like-containing domain superfamily
 IPR019559  Cullin protein, neddylation domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 cellular_componentGO:0031461 cullin-RING ubiquitin ligase complex IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA


Pathways (from Reactome)
Pathway description
Degradation of DVL
Hedgehog on state
Regulation of RAS by GAPs
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000007989 nedd8 / neural precursor cell expressed, developmentally down-regulated 8 / P29595* / Q15843*  / complex
 ENSDARG00000038967 cul3a / cullin 3a / CUL3* / Q13618* / Q9JLV5* / cullin 3*  / complex
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSDARG00000031203 commd1 / copper metabolism (Murr1) domain containing 1 / Q8K4M5* / Q8N668* / Gm28048* / COMM domain-containing protein 1 * / copper metabolism domain containing 1*  / complex / reaction
 ENSDARG00000078001 kbtbd7 / kelch repeat and BTB (POZ) domain containing 7 / Q86V97* / KBTBD6* / Q8WVZ9* / uncharacterized protein LOC432879 * / kelch repeat and BTB domain containing 7* / kelch repeat and BT...  / complex
 ENSDARG00000100108 cul3b / cullin 3b / CUL3* / Q13618* / Q9JLV5* / cullin 3*  / complex
 ENSDARG00000100519 spop / Q7T330 / speckle-type POZ protein / Gm5773* / Gm9117* / Gm9125* / O43791* / P0DMR5* / P0DMR6* / Tdpoz5* / Gm4778* / Gm4858* / Gm5286* / Q6YCH2* / Q6ZWS8* / Q717B2* / Q717B4* / Tdpoz1...  / complex






 

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