ENSDARG00000100519


Danio rerio

Features
Gene ID: ENSDARG00000100519
  
Biological name :spop
  
Synonyms : Q7T330 / speckle-type POZ protein / spop
  
Possible biological names infered from orthology : Gm10696 / Gm10697 / Gm37596 / Gm4778 / Gm4858 / Gm5286 / Gm5773 / Gm9117 / Gm9125 / Mus musculus speckle-type POZ protein (Spop), transcript variant 2, mRNA. / O43791 / P0DMR5 / P0DMR6 / predicted pseudogene 5773 / predicted pseudogene 9117 / Q6YCH2 / Q6ZWS8 / Q717B2 / Q717B4 / speckle type BTB/POZ protein / TD and POZ domain containing 5 / TD and POZ domain containing-like isoform 1 / TD and POZ domain-containing protein 1 / TD and POZ domain-containing protein 1-like / TD and POZ domain-containing protein 3 / TD and POZ domain-containing protein 4 / Tdpoz1 / Tdpoz2 / Tdpoz3 / Tdpoz4 / Tdpoz5
  
Species: Danio rerio
  
Chr. number: 3
Strand: -1
Band:
Gene start: 20658203
Gene end: 20793656
  
Corresponding Affymetrix probe sets: Dr.12893.1.S1_at (Zebrafish Array)   NM_201130_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000135804
Ensembl peptide - ENSDARP00000152225
Ensembl peptide - ENSDARP00000130146
NCBI entrez gene - 100005514     See in Manteia.
RefSeq - NM_201130
RefSeq Peptide - NP_957424
swissprot - A7YYH8
swissprot - Q7T330
ZFIN ID - ZDB-GENE-040426-1378
Ensembl - ENSDARG00000100519
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SPOPENSGALG00000009939Gallus gallus
 SPOPENSG00000121067Homo sapiens
 Gm10696ENSMUSG00000074424Mus musculus
 Gm10697ENSMUSG00000095251Mus musculus
 Gm37596ENSMUSG00000103350Mus musculus
 Gm4778ENSMUSG00000089696Mus musculus
 Gm4858ENSMUSG00000096879Mus musculus
 Gm5286ENSMUSG00000090268Mus musculus
 Gm5773ENSMUSG00000068879Mus musculus
 Gm9117ENSMUSG00000095822Mus musculus
 Gm9125ENSMUSG00000094328Mus musculus
 P0DMR5ENSMUSG00000094084Mus musculus
 Q6YCH2ENSMUSG00000060256Mus musculus
 Q717B4ENSMUSG00000058005Mus musculus
 SpopENSMUSG00000057522Mus musculus
 Tdpoz2ENSMUSG00000103362Mus musculus
 Tdpoz5ENSMUSG00000094163Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5BL35 / spoplb / spopla / speckle-type POZ protein-like a / SPOPL* / Q2M2N2* / Q6IQ16* / Speckle-type POZ protein-like * / speckle type BTB/POZ protein like*ENSDARG0000001056386
A0JMG1 / spoplb / speckle-type POZ protein-like bENSDARG0000000397484
si:dkey-260j18.2ENSDARG0000010194214
kbtbd4 / kelch repeat and BTB (POZ) domain containing 4 / Q9NVX7* / Q8R179* / kelch repeat and BTB domain containing 4* / Kelch repeat and BTB domain-containing protein 4 *ENSDARG0000006927113


Protein motifs (from Interpro)
Interpro ID Name
 IPR000210  BTB/POZ domain
 IPR002083  MATH/TRAF domain
 IPR008974  TRAF-like
 IPR011333  SKP1/BTB/POZ domain superfamily
 IPR034089  SPOP, C-terminal BACK-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030162 regulation of proteolysis IBA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process ISS
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0019005 SCF ubiquitin ligase complex IBA
 cellular_componentGO:0031463 Cul3-RING ubiquitin ligase complex ISS
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA


Pathways (from Reactome)
Pathway description
Hedgehog on state


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000037 anatomical structure anatomical structure apoptotic , abnormal
Show

 ZFA:0000128 midbrain midbrain apoptotic , abnormal
Show

 ZFA:0001094 whole organism whole organism decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010563 Q5BL35 / spoplb / spopla / speckle-type POZ protein-like a / SPOPL* / Q2M2N2* / Q6IQ16* / Speckle-type POZ protein-like * / speckle type BTB/POZ protein like*  / complex
 ENSDARG00000038967 cul3a / cullin 3a / CUL3* / Q13618* / Q9JLV5* / cullin 3*  / complex
 ENSDARG00000038030 rbx1 / ring-box 1, E3 ubiquitin protein ligase / P62878* / P62877* / ring-box 1* / E3 ubiquitin-protein ligase RBX1 E3 ubiquitin-protein ligase RBX1, N-terminally processed*  / complex
 ENSDARG00000100108 cul3b / cullin 3b / CUL3* / Q13618* / Q9JLV5* / cullin 3*  / complex
 ENSDARG00000100519 spop / Q7T330 / speckle-type POZ protein / Gm5773* / Gm9117* / Gm9125* / O43791* / P0DMR5* / P0DMR6* / Tdpoz5* / Gm4778* / Gm4858* / Gm5286* / Q6YCH2* / Q6ZWS8* / Q717B2* / Q717B4* / Tdpoz1...  / complex






 

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