ENSDARG00000039579


Danio rerio

Features
Gene ID: ENSDARG00000039579
  
Biological name :cfd
  
Synonyms : cfd / complement factor D (adipsin)
  
Possible biological names infered from orthology : complement factor D / P00746 / P03953
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 13681681
Gene end: 13684334
  
Corresponding Affymetrix probe sets: Dr.1999.1.S1_at (Zebrafish Array)   NM_001020532_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000057824
NCBI entrez gene - 553553     See in Manteia.
RefSeq - NM_001020532
RefSeq Peptide - NP_001018368
swissprot - Q6DBS8
ZFIN ID - ZDB-GENE-050522-411
Ensembl - ENSDARG00000039579
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CFDENSGALG00000040832Gallus gallus
 CFDENSG00000197766Homo sapiens
 CfdENSMUSG00000061780Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-21e2.13 / PRSS57* / Q14B24* / Q6UWY2* / serine protease 57*ENSDARG0000009484035
gzma / granzyme A / GZMK* / O35205* / P49863* / granzyme K*ENSDARG0000009038032
gzmk / granzyme K / O35205* / P49863*ENSDARG0000002878031
gzm3.3 / granzyme 3, tandem duplicate 3 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O351...ENSDARG0000009399031
gzm3 / granzyme 3, tandem duplicate 1 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O35164...ENSDARG0000007845130
gzm3.2 / granzyme 3, tandem duplicate 2 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O351...ENSDARG0000005598628
gzm3.4 / granzyme 3, tandem duplicate 4 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O351...ENSDARG0000007681428


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006957 complement activation, alternative pathway IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation
Alternative complement activation
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000005616 bfb / complement component bfb / CFB* / P04186* / P00751* / Gm20547* / AL645922.1* / complement factor B* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*  / reaction
 ENSDARG00000055278 cfb / complement factor B / P04186* / P00751* / Gm20547* / AL645922.1* / Complement factor B Complement factor B Ba fragment Complement factor B Bb fragment*  / reaction






 

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