ENSDARG00000078451


Danio rerio

Features
Gene ID: ENSDARG00000078451
  
Biological name :gzm3
  
Synonyms : granzyme 3, tandem duplicate 1 / gzm3
  
Possible biological names infered from orthology : cathepsin G / Chymase / chymase 1 / chymase 2, mast cell / CMA1 / Cma2 / CTSG / granzyme B / Granzyme C / Granzyme D / Granzyme E / Granzyme F / granzyme G / granzyme H / granzyme N / GZMB / Gzmc / Gzmd / Gzme / Gzmf / Gzmg / GZMH / Gzmn / Mast cell protease 1 / mast cell protease 2 / mast cell protease 4 / Mast cell protease 8 / Mast cell protease 9 / Mcpt1 / Mcpt2 / Mcpt4 / Mcpt8 / Mcpt9 / O35164 / P04187 / P08311 / P08882 / P08883 / P08884 / P10144 / P11033 / P11034 / P13366 / P15119 / P20718 / P21844 / P23946 / P28293 / P43430
  
Species: Danio rerio
  
Chr. number: 9
Strand: -1
Band:
Gene start: 32654554
Gene end: 32656656
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072861
NCBI entrez gene - 100000986     See in Manteia.
RefSeq - NM_001128550
RefSeq Peptide - NP_001122022
swissprot - A8WIQ2
ZFIN ID - ZDB-GENE-070912-132
Ensembl - ENSDARG00000078451
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000044661Gallus gallus
 CMA1ENSG00000092009Homo sapiens
 CTSGENSG00000100448Homo sapiens
 GZMBENSG00000100453Homo sapiens
 GZMHENSG00000100450Homo sapiens
 Cma1ENSMUSG00000022225Mus musculus
 Cma2ENSMUSG00000068289Mus musculus
 CtsgENSMUSG00000040314Mus musculus
 GzmbENSMUSG00000015437Mus musculus
 GzmcENSMUSG00000079186Mus musculus
 GzmdENSMUSG00000059256Mus musculus
 GzmeENSMUSG00000022156Mus musculus
 GzmfENSMUSG00000015441Mus musculus
 GzmgENSMUSG00000040284Mus musculus
 GzmnENSMUSG00000015443Mus musculus
 Mcpt1ENSMUSG00000022227Mus musculus
 Mcpt2ENSMUSG00000022226Mus musculus
 Mcpt4ENSMUSG00000061068Mus musculus
 Mcpt8ENSMUSG00000022157Mus musculus
 Mcpt9ENSMUSG00000071361Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gzm3.3 / granzyme 3, tandem duplicate 3 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O351...ENSDARG0000009399077
gzm3.4 / granzyme 3, tandem duplicate 4 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O351...ENSDARG0000007681450
gzm3.2 / granzyme 3, tandem duplicate 2 / CTSG* / Gzmc* / CMA1* / Cma2* / Gzmg* / Gzmf* / Gzme* / Gzmd* / GZMB* / Gzmn* / GZMH* / Mcpt4* / Mcpt8* / Mcpt2* / Mcpt1* / Mcpt9* / P43430* / O351...ENSDARG0000005598649
si:dkey-21e2.13 / PRSS57* / Q14B24* / Q6UWY2* / serine protease 57*ENSDARG0000009484035
gzma / granzyme A / GZMK* / O35205* / P49863* / granzyme K*ENSDARG0000009038030
gzmk / granzyme K / O35205* / P49863*ENSDARG0000002878029
cfd / complement factor D (adipsin) / P00746* / P03953* / complement factor D*ENSDARG0000003957929


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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