ENSMUSG00000022156


Mus musculus

Features
Gene ID: ENSMUSG00000022156
  
Biological name :Gzme
  
Synonyms : Granzyme E / Gzme / P08884
  
Possible biological names infered from orthology : granzyme H / GZMH / P20718
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C3
Gene start: 56117626
Gene end: 56120625
  
Corresponding Affymetrix probe sets: 10420268 (MoGene1.0st)   1421227_at (Mouse Genome 430 2.0 Array)   1450171_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000086978
NCBI entrez gene - 14942     See in Manteia.
MGI - MGI:109265
RefSeq - NM_010373
RefSeq Peptide - NP_034503
swissprot - P08884
Ensembl - ENSMUSG00000022156
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzm3ENSDARG00000078451Danio rerio
 gzm3.2ENSDARG00000055986Danio rerio
 gzm3.3ENSDARG00000093990Danio rerio
 gzm3.4ENSDARG00000076814Danio rerio
 ENSGALG00000044661Gallus gallus
 GZMHENSG00000100450Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gzmd / P11033 / Granzyme D / GZMH* / P20718* / granzyme H*ENSMUSG0000005925691
Gzmg / P13366 / granzyme G / GZMH* / P20718* / granzyme H*ENSMUSG0000004028482
Gzmf / P08883 / Granzyme F / GZMH* / P20718* / granzyme H*ENSMUSG0000001544176
Gzmn / granzyme N / GZMH* / P20718* / granzyme H*ENSMUSG0000001544371
Gzmc / P08882 / Granzyme C / GZMB* / P10144* / granzyme B*ENSMUSG0000007918658
Gzmb / P04187 / granzyme B / P10144*ENSMUSG0000001543755
Ctsg / P28293 / cathepsin G / P08311*ENSMUSG0000004031449
Mcpt4 / mast cell protease 4ENSMUSG0000006106847
Mcpt1 / P11034 / Mast cell protease 1 ENSMUSG0000002222746
Mcpt9 / O35164 / Mast cell protease 9 ENSMUSG0000007136146
Mcpt2 / P15119 / mast cell protease 2ENSMUSG0000002222645
Cma2 / chymase 2, mast cellENSMUSG0000006828945
Mcpt8 / P43430 / Mast cell protease 8 ENSMUSG0000002215744
Cma1 / P21844 / Chymase / P23946* / chymase 1*ENSMUSG0000002222542
Gzma / P11032 / Granzyme A / P12544*ENSMUSG0000002313238
Prss57 / Q14B24 / Serine protease 57 / Q6UWY2*ENSMUSG0000002032337
Gzmm / granzyme M isoform 2 / P51124* / granzyme M*ENSMUSG0000005420634
Gzmk / O35205 / Granzyme K / P49863*ENSMUSG0000004238533
Cfd / P03953 / Complement factor D / P00746*ENSMUSG0000006178030


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0019835 cytolysis IEA
 cellular_componentGO:0030141 secretory granule IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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