ENSMUSG00000022226


Mus musculus

Features
Gene ID: ENSMUSG00000022226
  
Biological name :Mcpt2
  
Synonyms : mast cell protease 2 / Mcpt2 / P15119
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C3
Gene start: 56042041
Gene end: 56044642
  
Corresponding Affymetrix probe sets: 10415438 (MoGene1.0st)   1449989_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015576
NCBI entrez gene - 17225     See in Manteia.
MGI - MGI:96938
RefSeq - NM_008571
RefSeq Peptide - NP_032597
swissprot - P15119
swissprot - Q541U2
Ensembl - ENSMUSG00000022226
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzm3ENSDARG00000078451Danio rerio
 gzm3.2ENSDARG00000055986Danio rerio
 gzm3.3ENSDARG00000093990Danio rerio
 gzm3.4ENSDARG00000076814Danio rerio
 ENSGALG00000044661Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mcpt1 / P11034 / Mast cell protease 1 ENSMUSG0000002222768
Mcpt4 / mast cell protease 4ENSMUSG0000006106867
Cma2 / chymase 2, mast cellENSMUSG0000006828961
Mcpt9 / O35164 / Mast cell protease 9 ENSMUSG0000007136161
Cma1 / P21844 / Chymase / P23946* / chymase 1*ENSMUSG0000002222549
Gzmf / P08883 / Granzyme F / GZMH* / P20718* / granzyme H*ENSMUSG0000001544148
Mcpt8 / P43430 / Mast cell protease 8 ENSMUSG0000002215748
Gzmg / P13366 / granzyme G / GZMH* / P20718* / granzyme H*ENSMUSG0000004028448
Gzmn / granzyme N / GZMH* / P20718* / granzyme H*ENSMUSG0000001544347
Gzmb / P04187 / granzyme B / P10144*ENSMUSG0000001543746
Gzme / P08884 / Granzyme E / GZMH* / P20718* / granzyme H*ENSMUSG0000002215646
Gzmd / P11033 / Granzyme D / GZMH* / P20718* / granzyme H*ENSMUSG0000005925645
Gzmc / P08882 / Granzyme C / GZMB* / P10144* / granzyme B*ENSMUSG0000007918645
Ctsg / P28293 / cathepsin G / P08311*ENSMUSG0000004031444
Gzma / P11032 / Granzyme A / P12544*ENSMUSG0000002313238
Gzmk / O35205 / Granzyme K / P49863*ENSMUSG0000004238537
Prss57 / Q14B24 / Serine protease 57 / Q6UWY2*ENSMUSG0000002032336
Gzmm / granzyme M isoform 2 / P51124* / granzyme M*ENSMUSG0000005420636
Cfd / P03953 / Complement factor D / P00746*ENSMUSG0000006178031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0030141 secretory granule IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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