ENSMUSG00000059256


Mus musculus

Features
Gene ID: ENSMUSG00000059256
  
Biological name :Gzmd
  
Synonyms : Granzyme D / Gzmd / P11033
  
Possible biological names infered from orthology : granzyme H / GZMH / P20718
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C3
Gene start: 56129556
Gene end: 56132608
  
Corresponding Affymetrix probe sets: 10420274 (MoGene1.0st)   1420343_at (Mouse Genome 430 2.0 Array)   1420344_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000080742
NCBI entrez gene - 14941     See in Manteia.
MGI - MGI:109255
RefSeq - NM_010372
RefSeq - XM_006518569
RefSeq Peptide - NP_034502
swissprot - P11033
Ensembl - ENSMUSG00000059256
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzm3ENSDARG00000078451Danio rerio
 gzm3.2ENSDARG00000055986Danio rerio
 gzm3.3ENSDARG00000093990Danio rerio
 gzm3.4ENSDARG00000076814Danio rerio
 ENSGALG00000044661Gallus gallus
 GZMHENSG00000100450Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gzme / P08884 / Granzyme E / GZMH* / P20718* / granzyme H*ENSMUSG0000002215690
Gzmg / P13366 / granzyme G / GZMH* / P20718* / granzyme H*ENSMUSG0000004028478
Gzmf / P08883 / Granzyme F / GZMH* / P20718* / granzyme H*ENSMUSG0000001544173
Gzmn / granzyme N / GZMH* / P20718* / granzyme H*ENSMUSG0000001544367
Gzmc / P08882 / Granzyme C / GZMB* / P10144* / granzyme B*ENSMUSG0000007918658
Gzmb / P04187 / granzyme B / P10144*ENSMUSG0000001543756
Ctsg / P28293 / cathepsin G / P08311*ENSMUSG0000004031447
Mcpt9 / O35164 / Mast cell protease 9 ENSMUSG0000007136145
Mcpt2 / P15119 / mast cell protease 2ENSMUSG0000002222644
Mcpt1 / P11034 / Mast cell protease 1 ENSMUSG0000002222744
Mcpt4 / mast cell protease 4ENSMUSG0000006106844
Cma2 / chymase 2, mast cellENSMUSG0000006828944
Mcpt8 / P43430 / Mast cell protease 8 ENSMUSG0000002215742
Cma1 / P21844 / Chymase / P23946* / chymase 1*ENSMUSG0000002222541
Gzma / P11032 / Granzyme A / P12544*ENSMUSG0000002313237
Prss57 / Q14B24 / Serine protease 57 / Q6UWY2*ENSMUSG0000002032335
Gzmk / O35205 / Granzyme K / P49863*ENSMUSG0000004238535
Gzmm / granzyme M isoform 2 / P51124* / granzyme M*ENSMUSG0000005420632
Cfd / P03953 / Complement factor D / P00746*ENSMUSG0000006178031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0019835 cytolysis IEA
 cellular_componentGO:0030141 secretory granule IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr