ENSGALG00000044661


Gallus gallus

Features
Gene ID: ENSGALG00000044661
  
Biological name :
  
Synonyms :
  
Possible biological names infered from orthology : cathepsin G / Chymase / chymase 1 / chymase 2, mast cell / CMA1 / Cma2 / CTSG / granzyme B / Granzyme C / Granzyme D / Granzyme E / Granzyme F / granzyme G / granzyme H / granzyme N / GZMB / Gzmc / Gzmd / Gzme / Gzmf / Gzmg / GZMH / Gzmn / Mast cell protease 1 / mast cell protease 2 / mast cell protease 4 / Mast cell protease 8 / Mast cell protease 9 / Mcpt1 / Mcpt2 / Mcpt4 / Mcpt8 / Mcpt9 / O35164 / P04187 / P08311 / P08882 / P08883 / P08884 / P10144 / P11033 / P11034 / P13366 / P15119 / P20718 / P21844 / P23946 / P28293 / P43430
  
Species: Gallus gallus
  
Chr. number: 28
Strand: -1
Band:
Gene start: 1271207
Gene end: 1272845
  
Corresponding Affymetrix probe sets: Gga.6553.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000062526
NCBI entrez gene - 426049     See in Manteia.
RefSeq - XM_423728
swissprot - A0A1L1RUM8
Ensembl - ENSGALG00000044661
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzm3ENSDARG00000078451Danio rerio
 gzm3.2ENSDARG00000055986Danio rerio
 gzm3.3ENSDARG00000093990Danio rerio
 gzm3.4ENSDARG00000076814Danio rerio
 CMA1ENSG00000092009Homo sapiens
 CTSGENSG00000100448Homo sapiens
 GZMBENSG00000100453Homo sapiens
 GZMHENSG00000100450Homo sapiens
 Cma1ENSMUSG00000022225Mus musculus
 Cma2ENSMUSG00000068289Mus musculus
 CtsgENSMUSG00000040314Mus musculus
 GzmbENSMUSG00000015437Mus musculus
 GzmcENSMUSG00000079186Mus musculus
 GzmdENSMUSG00000059256Mus musculus
 GzmeENSMUSG00000022156Mus musculus
 GzmfENSMUSG00000015441Mus musculus
 GzmgENSMUSG00000040284Mus musculus
 GzmnENSMUSG00000015443Mus musculus
 Mcpt1ENSMUSG00000022227Mus musculus
 Mcpt2ENSMUSG00000022226Mus musculus
 Mcpt4ENSMUSG00000061068Mus musculus
 Mcpt8ENSMUSG00000022157Mus musculus
 Mcpt9ENSMUSG00000071361Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GZMA / granzyme A precursor / P11032* / P12544* / granzyme A*ENSGALG0000001354842
ENSGALG0000001354637
PRSS57 / serine protease 57 / Q14B24* / Q6UWY2*ENSGALG0000003576237
GZMM* / P51124* / granzyme M* / granzyme M isoform 2 *ENSGALG0000001519235
CFD / complement factor D / P00746* / P03953*ENSGALG0000004083231


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IEA
 molecular_functionGO:0004252 serine-type endopeptidase activity IEA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Signaling by SCF-KIT
Degradation of the extracellular matrix
Activation of Matrix Metalloproteinases
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Neutrophil degranulation
Antimicrobial peptides
Activation, myristolyation of BID and translocation to mitochondria


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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