ENSMUSG00000040284


Mus musculus

Features
Gene ID: ENSMUSG00000040284
  
Biological name :Gzmg
  
Synonyms : granzyme G / Gzmg / P13366
  
Possible biological names infered from orthology : granzyme H / GZMH / P20718
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: C3
Gene start: 56156582
Gene end: 56159579
  
Corresponding Affymetrix probe sets: 10420280 (MoGene1.0st)   1422867_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000015578
NCBI entrez gene - 14944     See in Manteia.
MGI - MGI:109253
RefSeq - NM_010375
RefSeq Peptide - NP_034505
swissprot - P13366
swissprot - Q4KL28
Ensembl - ENSMUSG00000040284
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzm3ENSDARG00000078451Danio rerio
 gzm3.2ENSDARG00000055986Danio rerio
 gzm3.3ENSDARG00000093990Danio rerio
 gzm3.4ENSDARG00000076814Danio rerio
 ENSGALG00000044661Gallus gallus
 GZMHENSG00000100450Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gzme / P08884 / Granzyme E / GZMH* / P20718* / granzyme H*ENSMUSG0000002215682
Gzmf / P08883 / Granzyme F / GZMH* / P20718* / granzyme H*ENSMUSG0000001544180
Gzmd / P11033 / Granzyme D / GZMH* / P20718* / granzyme H*ENSMUSG0000005925679
Gzmn / granzyme N / GZMH* / P20718* / granzyme H*ENSMUSG0000001544370
Gzmc / P08882 / Granzyme C / GZMB* / P10144* / granzyme B*ENSMUSG0000007918661
Gzmb / P04187 / granzyme B / P10144*ENSMUSG0000001543758
Ctsg / P28293 / cathepsin G / P08311*ENSMUSG0000004031449
Mcpt4 / mast cell protease 4ENSMUSG0000006106848
Mcpt2 / P15119 / mast cell protease 2ENSMUSG0000002222647
Mcpt1 / P11034 / Mast cell protease 1 ENSMUSG0000002222747
Mcpt9 / O35164 / Mast cell protease 9 ENSMUSG0000007136147
Mcpt8 / P43430 / Mast cell protease 8 ENSMUSG0000002215746
Cma2 / chymase 2, mast cellENSMUSG0000006828946
Cma1 / P21844 / Chymase / P23946* / chymase 1*ENSMUSG0000002222543
Prss57 / Q14B24 / Serine protease 57 / Q6UWY2*ENSMUSG0000002032338
Gzma / P11032 / Granzyme A / P12544*ENSMUSG0000002313237
Gzmm / granzyme M isoform 2 / P51124* / granzyme M*ENSMUSG0000005420636
Gzmk / O35205 / Granzyme K / P49863*ENSMUSG0000004238535
Cfd / P03953 / Complement factor D / P00746*ENSMUSG0000006178032


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 biological_processGO:0019835 cytolysis IEA
 cellular_componentGO:0030141 secretory granule IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Metabolism of Angiotensinogen to Angiotensins
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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