ENSMUSG00000068289


Mus musculus

Features
Gene ID: ENSMUSG00000068289
  
Biological name :Cma2
  
Synonyms : chymase 2, mast cell / Cma2
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C3
Gene start: 55950980
Gene end: 55974031
  
Corresponding Affymetrix probe sets: 10415425 (MoGene1.0st)   10420241 (MoGene1.0st)   1450538_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000086984
Ensembl peptide - ENSMUSP00000154424
NCBI entrez gene - 545055     See in Manteia.
MGI - MGI:88426
RefSeq - XM_006519283
RefSeq - NM_001024714
RefSeq Peptide - NP_001019885
swissprot - Q91VB1
Ensembl - ENSMUSG00000068289
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gzm3ENSDARG00000078451Danio rerio
 gzm3.2ENSDARG00000055986Danio rerio
 gzm3.3ENSDARG00000093990Danio rerio
 gzm3.4ENSDARG00000076814Danio rerio
 ENSGALG00000044661Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Mcpt9 / O35164 / Mast cell protease 9 ENSMUSG0000007136195
Mcpt4 / mast cell protease 4ENSMUSG0000006106871
Mcpt1 / P11034 / Mast cell protease 1 ENSMUSG0000002222769
Mcpt2 / P15119 / mast cell protease 2ENSMUSG0000002222661
Cma1 / P21844 / Chymase / P23946* / chymase 1*ENSMUSG0000002222552
Gzmf / P08883 / Granzyme F / GZMH* / P20718* / granzyme H*ENSMUSG0000001544148
Gzmg / P13366 / granzyme G / GZMH* / P20718* / granzyme H*ENSMUSG0000004028447
Gzmc / P08882 / Granzyme C / GZMB* / P10144* / granzyme B*ENSMUSG0000007918647
Gzmb / P04187 / granzyme B / P10144*ENSMUSG0000001543746
Gzme / P08884 / Granzyme E / GZMH* / P20718* / granzyme H*ENSMUSG0000002215646
Ctsg / P28293 / cathepsin G / P08311*ENSMUSG0000004031446
Gzmn / granzyme N / GZMH* / P20718* / granzyme H*ENSMUSG0000001544345
Gzmd / P11033 / Granzyme D / GZMH* / P20718* / granzyme H*ENSMUSG0000005925645
Mcpt8 / P43430 / Mast cell protease 8 ENSMUSG0000002215744
Gzma / P11032 / Granzyme A / P12544*ENSMUSG0000002313237
Prss57 / Q14B24 / Serine protease 57 / Q6UWY2*ENSMUSG0000002032336
Gzmk / O35205 / Granzyme K / P49863*ENSMUSG0000004238536
Gzmm / granzyme M isoform 2 / P51124* / granzyme M*ENSMUSG0000005420635
Cfd / P03953 / Complement factor D / P00746*ENSMUSG0000006178030


Protein motifs (from Interpro)
Interpro ID Name
 IPR001254  Serine proteases, trypsin domain
 IPR001314  Peptidase S1A, chymotrypsin family
 IPR009003  Peptidase S1, PA clan
 IPR018114  Serine proteases, trypsin family, histidine active site
 IPR033116  Serine proteases, trypsin family, serine active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006508 proteolysis IBA
 cellular_componentGO:0030141 secretory granule IBA
 molecular_functionGO:0004252 serine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008236 serine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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