ENSDARG00000042726


Danio rerio

Features
Gene ID: ENSDARG00000042726
  
Biological name :si:ch211-253b1.3
  
Synonyms : si:ch211-253b1.3
  
Possible biological names infered from orthology : GRB7 / growth factor receptor bound protein 7 / Q03160 / Q14451
  
Species: Danio rerio
  
Chr. number: 24
Strand: 1
Band:
Gene start: 36414829
Gene end: 36442590
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000062698
swissprot - F1QD02
ZFIN ID - ZDB-GENE-091118-23
Ensembl - ENSDARG00000042726
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GRB7ENSGALG00000036500Gallus gallus
 GRB7ENSG00000141738Homo sapiens
 Grb7ENSMUSG00000019312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
grb10b / growth factor receptor-bound protein 10b / GRB10* / Q60760* / Q13322* / growth factor receptor bound protein 10*ENSDARG0000003530848
grb10a / growth factor receptor-bound protein 10a / GRB10* / Q60760* / Q13322* / growth factor receptor bound protein 10*ENSDARG0000000201347
GRB14 / growth factor receptor bound protein 14 / Q14449*ENSDARG0000006828031
raph1a / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1a / RAPH1* / Q70E73* / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1*ENSDARG0000000630121
apbb1ip / amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein / Q7Z5R6* / Q8R5A3* / amyloid beta precursor protein binding family B member 1 interacting protein*ENSDARG0000001650521
raph1b / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1b / RAPH1* / Q70E73* / Ras association (RalGDS/AF-6) and pleckstrin homology domains 1*ENSDARG0000006173221


Protein motifs (from Interpro)
Interpro ID Name
 IPR000159  Ras-associating (RA) domain
 IPR000980  SH2 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR015042  BPS (Between PH and SH2) domain
 IPR029071  Ubiquitin-like domain superfamily
 IPR035032  Growth factor receptor-bound protein 7


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IEA


Pathways (from Reactome)
Pathway description
GRB7 events in ERBB2 signaling
Downstream signal transduction
Tie2 Signaling
RET signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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