ENSDARG00000043250


Danio rerio

Features
Gene ID: ENSDARG00000043250
  
Biological name :ppm1ab
  
Synonyms : ppm1ab / protein phosphatase, Mg2+/Mn2+ dependent, 1Ab
  
Possible biological names infered from orthology : P35813 / P49443 / PPM1A / protein phosphatase 1A, magnesium dependent, alpha isoform / protein phosphatase, Mg2+/Mn2+ dependent 1A
  
Species: Danio rerio
  
Chr. number: 20
Strand: -1
Band:
Gene start: 20600971
Gene end: 20611063
  
Corresponding Affymetrix probe sets: Dr.20992.1.S1_at (Zebrafish Array)   
  
Cross references: Ensembl peptide - ENSDARP00000146872
Ensembl peptide - ENSDARP00000063491
NCBI entrez gene - 30703     See in Manteia.
RefSeq - NM_001161332
RefSeq - XM_005160487
RefSeq Peptide - NP_001154804
swissprot - Q5TZI2
swissprot - A0JMI7
ZFIN ID - ZDB-GENE-991102-14
Ensembl - ENSDARG00000043250
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PPM1AENSGALG00000011917Gallus gallus
 PPM1AENSG00000100614Homo sapiens
 Ppm1aENSMUSG00000021096Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ppm1aa / protein phosphatase, Mg2+/Mn2+ dependent, 1Aa / PPM1A* / P49443* / P35813* / protein phosphatase, Mg2+/Mn2+ dependent 1A* / protein phosphatase 1A, magnesium dependent, alpha isoform*ENSDARG0000003215579
ppm1bb / protein phosphatase, Mg2+/Mn2+ dependent, 1Bb / PPM1B* / P36993* / O75688* / protein phosphatase, Mg2+/Mn2+ dependent 1B* / protein phosphatase 1B, magnesium dependent, beta isoform*ENSDARG0000001149667
ppm1ba / protein phosphatase, Mg2+/Mn2+ dependent, 1Ba / PPM1B* / P36993* / O75688* / protein phosphatase, Mg2+/Mn2+ dependent 1B* / protein phosphatase 1B, magnesium dependent, beta isoform*ENSDARG0000000188866
ppm1na / protein phosphatase, Mg2+/Mn2+ dependent, 1Na (putative) / PPM1N* / Q8BGL1* / Q8N819* / Probable protein phosphatase 1N * / protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)*ENSDARG0000001023149
ppm1nb / protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative) / PPM1N* / Q8BGL1* / Q8N819* / Probable protein phosphatase 1N * / protein phosphatase, Mg2+/Mn2+ dependent 1N (putative)*ENSDARG0000005703248


Protein motifs (from Interpro)
Interpro ID Name
 IPR000222  PPM-type phosphatase, divalent cation binding
 IPR001932  PPM-type phosphatase domain
 IPR012911  Protein serine/threonine phosphatase 2C, C-terminal
 IPR015655  Protein phosphatase 2C family


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity IEA
 molecular_functionGO:0004722 protein serine/threonine phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0030145 manganese ion binding IEA
 molecular_functionGO:0043169 cation binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Downregulation of SMAD2/3:SMAD4 transcriptional activity
Energy dependent regulation of mTOR by LKB1-AMPK


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr