ENSDARG00000043548


Danio rerio

Features
Gene ID: ENSDARG00000043548
  
Biological name :atg4da
  
Synonyms : atg4da / autophagy related 4D, cysteine peptidase a
  
Possible biological names infered from orthology : ATG4D / autophagy related 4D cysteine peptidase / Cysteine protease ATG4D Cysteine protease ATG4D, mitochondrial / Q86TL0 / Q8BGV9
  
Species: Danio rerio
  
Chr. number: 1
Strand: 1
Band:
Gene start: 51386649
Gene end: 51406531
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000126975
Ensembl peptide - ENSDARP00000063935
NCBI entrez gene - 795933     See in Manteia.
RefSeq - XM_009294436
RefSeq - XM_009294437
swissprot - E7F0L9
ZFIN ID - ZDB-GENE-041111-102
Ensembl - ENSDARG00000043548
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ATG4DENSG00000130734Homo sapiens
 Atg4dENSMUSG00000002820Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
atg4c / autophagy related 4C, cysteine peptidase / Q811C2* / Q96DT6* / Cysteine protease ATG4C *ENSDARG0000004437343
atg4db / autophagy related 4D, cysteine peptidase b / ATG4D* / Q8BGV9* / Q86TL0* / autophagy related 4D cysteine peptidase* / Cysteine protease ATG4D Cysteine protease ATG4D, mitochondrial*ENSDARG0000008814541
atg4b / Q6DG88 / autophagy related 4B, cysteine peptidase / Q9Y4P1*ENSDARG0000005210424
atg4a / autophagy related 4A, cysteine peptidase / Q8WYN0*ENSDARG0000001453123


Protein motifs (from Interpro)
Interpro ID Name
 IPR005078  Peptidase C54


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000045 autophagosome assembly IBA
 biological_processGO:0000422 autophagy of mitochondrion IBA
 biological_processGO:0006501 C-terminal protein lipidation IBA
 biological_processGO:0006508 proteolysis IEA
 biological_processGO:0006612 protein targeting to membrane IBA
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0021702 cerebellar Purkinje cell differentiation IMP
 biological_processGO:0044804 autophagy of nucleus IBA
 biological_processGO:0051697 protein delipidation IBA
 biological_processGO:0098749 cerebellar neuron development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004197 cysteine-type endopeptidase activity IBA
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA


Pathways (from Reactome)
Pathway description
Macroautophagy


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
brain hydrocephalic , abnormal
Show

 ZFA:0000012 central nervous system central nervous system degenerate , abnormal
central nervous system malformed , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0001691 cerebellar granule cell cerebellar granule cell decreased amount , abnormal
Show

 ZFA:0009071 Purkinje cell Purkinje cell decreased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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