ENSDARG00000043976


Danio rerio

Features
Gene ID: ENSDARG00000043976
  
Biological name :etf1b
  
Synonyms : etf1b / eukaryotic translation termination factor 1b
  
Possible biological names infered from orthology : ETF1 / Eukaryotic peptide chain release factor subunit 1 / eukaryotic translation termination factor 1 / P62495 / Q8BWY3
  
Species: Danio rerio
  
Chr. number: 10
Strand: 1
Band:
Gene start: 21434649
Gene end: 21444731
  
Corresponding Affymetrix probe sets: Dr.21285.1.A1_at (Zebrafish Array)   Dr.21285.1.A1_x_at (Zebrafish Array)   Dr.4113.1.S1_at (Zebrafish Array)   Dr.4113.1.S2_at (Zebrafish Array)   NM_201460_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000064557
Ensembl peptide - ENSDARP00000146923
NCBI entrez gene - 266989     See in Manteia.
RefSeq - XM_021479101
RefSeq - NM_201460
RefSeq Peptide - NP_958868
swissprot - Q803E5
ZFIN ID - ZDB-GENE-021029-1
Ensembl - ENSDARG00000043976
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ETF1ENSGALG00000002262Gallus gallus
 ETF1ENSG00000120705Homo sapiens
 Etf1ENSMUSG00000024360Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
etf1a / eukaryotic translation termination factor 1a / ETF1* / P62495* / eukaryotic translation termination factor 1*ENSDARG0000010521084


Protein motifs (from Interpro)
Interpro ID Name
 IPR004403  Peptide chain release factor eRF1/aRF1
 IPR005140  eRF1 domain 1/Pelota-like
 IPR005141  eRF1 domain 2
 IPR005142  eRF1 domain 3
 IPR024049  Peptide Chain Release Factor eRF1/aRF1, N-terminal
 IPR029064  50S ribosomal protein L30e-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006415 translational termination IEA
 biological_processGO:0007420 brain development IMP
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003747 translation release factor activity IEA


Pathways (from Reactome)
Pathway description
Eukaryotic Translation Termination
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
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 ZFA:0000012 central nervous system central nervous system decreased thickness , abnormal
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 ZFA:0000107 eye eye decreased size , abnormal
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 ZFA:0000135 notochord notochord bent , abnormal
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 ZFA:0001094 whole organism whole organism morphology , abnormal
whole organism decreased size , abnormal
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 ZFA:0001114 head head decreased size , abnormal
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 ZFA:0001115 trunk trunk curved ventral , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000031048 gspt1 / G1 to S phase transition 1 / GSPT2* / P15170* / Q149F3* / Q8IYD1* / Q8R050* / G1 to S phase transition 2*  / complex
 ENSDARG00000043976 etf1b / eukaryotic translation termination factor 1b / ETF1* / Q8BWY3* / P62495* / eukaryotic translation termination factor 1* / Eukaryotic peptide chain release factor subunit 1 *  / complex
 ENSDARG00000098627 gspt1l / G1 to S phase transition 1, like / GSPT1* / GSPT2* / P15170* / Q149F3* / Q8IYD1* / Q8R050* / G1 to S phase transition 1* / G1 to S phase transition 2*  / complex
 ENSDARG00000071878 trmt112 / tRNA methyltransferase 11-2 homolog (S. cerevisiae) / Q9UI30* / Q9DCG9* / tRNA methyltransferase 11-2* / tRNA methyltransferase subunit 11-2*  / reaction






 

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