ENSDARG00000031048


Danio rerio

Features
Gene ID: ENSDARG00000031048
  
Biological name :gspt1
  
Synonyms : G1 to S phase transition 1 / gspt1
  
Possible biological names infered from orthology : G1 to S phase transition 2 / GSPT2 / P15170 / Q149F3 / Q8IYD1 / Q8R050
  
Species: Danio rerio
  
Chr. number: 12
Strand: 1
Band:
Gene start: 19362335
Gene end: 19383945
  
Corresponding Affymetrix probe sets: Dr.13814.1.S1_at (Zebrafish Array)   Dr.17154.1.A1_at (Zebrafish Array)   NM_001003992_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000041710
Ensembl peptide - ENSDARP00000156620
NCBI entrez gene - 445485     See in Manteia.
RefSeq - NM_001003992
RefSeq Peptide - NP_001003992
swissprot - Q68EH0
ZFIN ID - ZDB-GENE-040822-36
Ensembl - ENSDARG00000031048
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 GSPT1ENSGALG00000039500Gallus gallus
 GSPT1ENSG00000103342Homo sapiens
 GSPT2ENSG00000189369Homo sapiens
 Gspt1ENSMUSG00000062203Mus musculus
 Gspt2ENSMUSG00000071723Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
gspt1l / G1 to S phase transition 1, like / GSPT1* / GSPT2* / P15170* / Q149F3* / Q8IYD1* / Q8R050* / G1 to S phase transition 1* / G1 to S phase transition 2*ENSDARG0000009862782
hbs1l / HBS1-like translational GTPase / Q69ZS7* / Q9Y450* / HBS1-like protein *ENSDARG0000003677833


Protein motifs (from Interpro)
Interpro ID Name
 IPR000795  Transcription factor, GTP-binding domain
 IPR004160  Translation elongation factor EFTu/EF1A, C-terminal
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR009001  Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
 IPR009818  Ataxin-2, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031157  Tr-type G domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002184 cytoplasmic translational termination IBA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0018444 translation release factor complex IBA
 molecular_functionGO:0003747 translation release factor activity IBA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Eukaryotic Translation Termination
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000043976 etf1b / eukaryotic translation termination factor 1b / ETF1* / Q8BWY3* / P62495* / eukaryotic translation termination factor 1* / Eukaryotic peptide chain release factor subunit 1 *  / complex
 ENSDARG00000071878 trmt112 / tRNA methyltransferase 11-2 homolog (S. cerevisiae) / Q9UI30* / Q9DCG9* / tRNA methyltransferase 11-2* / tRNA methyltransferase subunit 11-2*  / reaction






 

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