ENSMUSG00000071723


Mus musculus

Features
Gene ID: ENSMUSG00000071723
  
Biological name :Gspt2
  
Synonyms : G1 to S phase transition 2 / Gspt2 / Q149F3
  
Possible biological names infered from orthology : Q8IYD1
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: C3
Gene start: 94636069
Gene end: 94643244
  
Corresponding Affymetrix probe sets: 10600814 (MoGene1.0st)   1418109_at (Mouse Genome 430 2.0 Array)   1455721_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109523
Ensembl peptide - ENSMUSP00000139286
NCBI entrez gene - 14853     See in Manteia.
MGI - MGI:1316727
RefSeq - NM_008179
RefSeq Peptide - NP_032205
swissprot - Q149F3
swissprot - Q8BQF5
Ensembl - ENSMUSG00000071723
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gspt1ENSDARG00000031048Danio rerio
 gspt1lENSDARG00000098627Danio rerio
 GSPT1ENSGALG00000039500Gallus gallus
 GSPT2ENSG00000189369Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gspt1 / Q8R050 / G1 to S phase transition 1 / P15170*ENSMUSG0000006220384
Hbs1l / Q69ZS7 / HBS1-like protein / Q9Y450* / HBS1 like translational GTPase*ENSMUSG0000001997732


Protein motifs (from Interpro)
Interpro ID Name
 IPR000795  Transcription factor, GTP-binding domain
 IPR004160  Translation elongation factor EFTu/EF1A, C-terminal
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR009001  Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
 IPR009818  Ataxin-2, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031157  Tr-type G domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0002184 cytoplasmic translational termination IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0007049 cell cycle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0018444 translation release factor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003747 translation release factor activity IBA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Eukaryotic Translation Termination
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000044442 N6amt1 / N-6 adenine-specific DNA methyltransferase 1 (putative) / Q9Y5N5* / N-6 adenine-specific DNA methyltransferase 1*  / reaction
 ENSMUSG00000038812 Q9DCG9 / Trmt112 / tRNA methyltransferase 11-2 / Q9UI30* / tRNA methyltransferase subunit 11-2*  / reaction
 ENSMUSG00000024360 Etf1 / Q8BWY3 / Eukaryotic peptide chain release factor subunit 1 / P62495* / eukaryotic translation termination factor 1*  / complex






 

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