ENSMUSG00000062203


Mus musculus

Features
Gene ID: ENSMUSG00000062203
  
Biological name :Gspt1
  
Synonyms : G1 to S phase transition 1 / Gspt1 / Q8R050
  
Possible biological names infered from orthology : P15170
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A1
Gene start: 11219292
Gene end: 11254325
  
Corresponding Affymetrix probe sets: 10437748 (MoGene1.0st)   1426736_at (Mouse Genome 430 2.0 Array)   1426737_at (Mouse Genome 430 2.0 Array)   1435000_at (Mouse Genome 430 2.0 Array)   1446550_at (Mouse Genome 430 2.0 Array)   1452168_x_at (Mouse Genome 430 2.0 Array)   1455173_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000078940
Ensembl peptide - ENSMUSP00000130583
Ensembl peptide - ENSMUSP00000130959
NCBI entrez gene - 14852     See in Manteia.
MGI - MGI:1316728
RefSeq - NM_001130008
RefSeq - NM_146066
RefSeq Peptide - NP_001123480
RefSeq Peptide - NP_666178
swissprot - F7CE88
swissprot - Q8R050
Ensembl - ENSMUSG00000062203
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gspt1ENSDARG00000031048Danio rerio
 gspt1lENSDARG00000098627Danio rerio
 GSPT1ENSGALG00000039500Gallus gallus
 GSPT1ENSG00000103342Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gspt2 / Q149F3 / G1 to S phase transition 2 / Q8IYD1*ENSMUSG0000007172383
Hbs1l / Q69ZS7 / HBS1-like protein / Q9Y450* / HBS1 like translational GTPase*ENSMUSG0000001997733


Protein motifs (from Interpro)
Interpro ID Name
 IPR000795  Transcription factor, GTP-binding domain
 IPR004160  Translation elongation factor EFTu/EF1A, C-terminal
 IPR004161  Translation elongation factor EFTu-like, domain 2
 IPR009000  Translation protein, beta-barrel domain superfamily
 IPR009001  Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
 IPR009818  Ataxin-2, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR031157  Tr-type G domain, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0002184 cytoplasmic translational termination IBA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006479 protein methylation IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0018444 translation release factor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003747 translation release factor activity IEA
 molecular_functionGO:0003924 GTPase activity IBA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Eukaryotic Translation Termination
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000044442 N6amt1 / N-6 adenine-specific DNA methyltransferase 1 (putative) / Q9Y5N5* / N-6 adenine-specific DNA methyltransferase 1*  / reaction
 ENSMUSG00000038812 Q9DCG9 / Trmt112 / tRNA methyltransferase 11-2 / Q9UI30* / tRNA methyltransferase subunit 11-2*  / reaction
 ENSMUSG00000024360 Etf1 / Q8BWY3 / Eukaryotic peptide chain release factor subunit 1 / P62495* / eukaryotic translation termination factor 1*  / complex






 

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