ENSDARG00000045015


Danio rerio

Features
Gene ID: ENSDARG00000045015
  
Biological name :cyp27b1
  
Synonyms : cyp27b1 / cytochrome P450, family 27, subfamily B, polypeptide 1
  
Possible biological names infered from orthology : 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial / cytochrome P450 family 27 subfamily B member 1 / O15528 / O35084
  
Species: Danio rerio
  
Chr. number: 11
Strand: 1
Band:
Gene start: 329687
Gene end: 339847
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000142417
NCBI entrez gene - 793309     See in Manteia.
RefSeq - NM_001311791
RefSeq Peptide - NP_001298720
swissprot - A0A140LGN8
ZFIN ID - ZDB-GENE-111005-2
Ensembl - ENSDARG00000045015
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 O15528ENSG00000111012Homo sapiens
 O35084ENSMUSG00000006724Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
si:dkey-91i10.3ENSDARG0000005726243
si:ch211-113j14.1ENSDARG0000007376441
A8WGA0 / cyp27c1 / cytochrome P450, family 27, subfamily C, polypeptide 1 / Q4G0S4* / cytochrome P450 family 27 subfamily C member 1*ENSDARG0000009266041
cyp27a7 / cytochrome P450, family 27, subfamily A, polypeptide 7 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000003380240
cyp27a1.2 / cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000006918638
zgc:136333 / CYP27A1 (1 of many) / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000008801338
cyp27a1.4 / cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000005515937
cyp24a1 / cytochrome P450, family 24, subfamily A, polypeptide 1 / Q07973* / Q64441* / cytochrome P450 family 24 subfamily A member 1* / 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial *ENSDARG0000010327730
cyp11a1 / cytochrome P450, family 11, subfamily A, polypeptide 1 / P05108* / Q9QZ82* / cytochrome P450 family 11 subfamily A member 1* / Cholesterol side-chain cleavage enzyme, mitochondrial *ENSDARG0000000234727
cyp11a2 / cytochrome P450, family 11, subfamily A, polypeptide 2 / Q9QZ82* / P05108* / CYP11A1* / cytochrome P450 family 11 subfamily A member 1* / Cholesterol side-chain cleavage enzyme, m...ENSDARG0000009269627
cyp11c1 / cytochrome P450, family 11, subfamily C, polypeptide 1 / P19099* / P15538* / CYP11B1* / CYP11B2* / cytochrome P450 family 11 subfamily B member 2* / cytochrome P450 family 11 subf...ENSDARG0000004201426
cyp3a65 / cytochrome P450, family 3, subfamily A, polypeptide 65 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readth...ENSDARG0000010329522
tbxas1 / thromboxane A synthase 1 (platelet) / P24557* / P36423* / thromboxane A synthase 1*ENSDARG0000000224921
cyp3c1 / cytochrome P450, family 3, subfamily c, polypeptide 1 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000001557521
cyp3c3 / cytochrome P450, family 3, subfamily c, polypeptide 3 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000003787321
cyp3c4 / cytochrome P450, family 3, subfamily C, polypeptide 4 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000007002121
cyp3c3 / cyp3c2 / cytochrome P450, family 3, subfamily c, polypeptide 2 / P08684* / O09158* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / P20815* / P2446...ENSDARG0000003787420
cyp46a1.1 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 / Q9Y6A2* / Q9WVK8* / CYP46A1* / Cholesterol 24-hydroxylase * / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000001213719
cyp46a1.3 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000008917719
cyp46a1.2 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000000426218


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0036378 calcitriol biosynthetic process from calciol IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071425 hematopoietic stem cell proliferation IMP
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0004498 calcidiol 1-monooxygenase activity IDA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Vitamin D (calciferol) metabolism
Vitamins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0005028 ventral wall of dorsal aorta ventral wall of dorsal aorta has fewer parts of type hematopoietic multipotent progenitor cell , abnormal
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Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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