ENSDARG00000103295


Danio rerio

Features
Gene ID: ENSDARG00000103295
  
Biological name :cyp3a65
  
Synonyms : cyp3a65 / cytochrome P450, family 3, subfamily A, polypeptide 65
  
Possible biological names infered from orthology : Cyp3a11 / Cyp3a13 / Cyp3a16 / Cyp3a25 / CYP3A4 / Cyp3a41a / Cyp3a41b / CYP3A43 / Cyp3a44 / CYP3A5 / Cyp3a57 / Cyp3a59 / CYP3A7 / CYP3A7-CYP3A51P / CYP3A7-CYP3A51P readthrough / Cytochrome P450 3A11 / Cytochrome P450 3A13 / Cytochrome P450 3A16 / Cytochrome P450 3A25 / Cytochrome P450 3A41 / cytochrome P450 family 3 subfamily A member 4 / cytochrome P450 family 3 subfamily A member 43 / cytochrome P450 family 3 subfamily A member 5 / cytochrome P450 family 3 subfamily A member 7 / cytochrome P450, family 3, subfamily a, polypeptide 44 / cytochrome P450, family 3, subfamily a, polypeptide 57 / cytochrome P450, family 3, subfamily a, polypeptide 59 / O09158 / P08684 / P20815 / P24462 / Q64459 / Q64464 / Q64481 / Q9HB55 / Q9JMA7
  
Species: Danio rerio
  
Chr. number: 1
Strand: -1
Band:
Gene start: 59338175
Gene end: 59348118
  
Corresponding Affymetrix probe sets: Dr.25208.1.A1_at (Zebrafish Array)   Dr.25208.2.S1_at (Zebrafish Array)   NM_001037438_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000137034
NCBI entrez gene - 553969     See in Manteia.
RefSeq - NM_001037438
RefSeq Peptide - NP_001032515
swissprot - A0A0R4IQY0
ZFIN ID - ZDB-GENE-050604-1
Ensembl - ENSDARG00000103295
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP3A4ENSGALG00000004436Gallus gallus
 CYP3A5ENSGALG00000004449Gallus gallus
 CYP3A4ENSG00000160868Homo sapiens
 CYP3A5ENSG00000106258Homo sapiens
 CYP3A7ENSG00000160870Homo sapiens
 P24462ENSG00000282301Homo sapiens
 Q9HB55ENSG00000021461Homo sapiens
 Cyp3a44ENSMUSG00000054417Mus musculus
 Cyp3a57ENSMUSG00000070419Mus musculus
 Cyp3a59ENSMUSG00000061292Mus musculus
 O09158ENSMUSG00000029630Mus musculus
 Q64459ENSMUSG00000056035Mus musculus
 Q64464ENSMUSG00000029727Mus musculus
 Q64481ENSMUSG00000038656Mus musculus
 Q9JMA7ENSMUSG00000075552Mus musculus
 Q9JMA7ENSMUSG00000075551Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
cyp3c3 / cytochrome P450, family 3, subfamily c, polypeptide 3 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000003787353
cyp3c1 / cytochrome P450, family 3, subfamily c, polypeptide 1 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000001557552
cyp3c3 / cyp3c2 / cytochrome P450, family 3, subfamily c, polypeptide 2 / P08684* / O09158* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / P20815* / P2446...ENSDARG0000003787451
cyp3c4 / cytochrome P450, family 3, subfamily C, polypeptide 4 / P20815* / P08684* / O09158* / P24462* / Q64459* / Q9JMA7* / CYP3A5* / Q9HB55* / CYP3A4* / CYP3A7* / Q64481* / Q64464* / Cyp3...ENSDARG0000007002151
tbxas1 / thromboxane A synthase 1 (platelet) / P24557* / P36423* / thromboxane A synthase 1*ENSDARG0000000224936
cyp46a1.1 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 / Q9Y6A2* / Q9WVK8* / CYP46A1* / Cholesterol 24-hydroxylase * / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000001213725
cyp46a1.1 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000009347724
cyp46a1.2 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 2 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000000426222
cyp46a1.3 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 3 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000008917722
A8WGA0 / cyp27c1 / cytochrome P450, family 27, subfamily C, polypeptide 1 / Q4G0S4* / cytochrome P450 family 27 subfamily C member 1*ENSDARG0000009266022
cyp46a1.4 / cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 4 / Q9Y6A2* / CYP46A1* / cytochrome P450 family 46 subfamily A member 1*ENSDARG0000011382022
cyp27b1 / cytochrome P450, family 27, subfamily B, polypeptide 1 / O15528* / O35084* / cytochrome P450 family 27 subfamily B member 1* / 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial *ENSDARG0000004501521
si:dkey-91i10.3ENSDARG0000005726221
si:ch211-113j14.1ENSDARG0000007376421
cyp27a7 / cytochrome P450, family 27, subfamily A, polypeptide 7 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000003380219
cyp27a1.4 / cytochrome P450, family 27, subfamily A, polypeptide 1, gene 4 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000005515919
cyp27a1.2 / cytochrome P450, family 27, subfamily A, polypeptide 1, gene 2 / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000006918619
zgc:136333 / CYP27A1 (1 of many) / Q02318* / Q9DBG1* / CYP27A1* / Sterol 26-hydroxylase, mitochondrial * / cytochrome P450 family 27 subfamily A member 1*ENSDARG0000008801319
cyp24a1 / cytochrome P450, family 24, subfamily A, polypeptide 1 / Q07973* / Q64441* / cytochrome P450 family 24 subfamily A member 1* / 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial *ENSDARG0000010327719
cyp11a1 / cytochrome P450, family 11, subfamily A, polypeptide 1 / P05108* / Q9QZ82* / cytochrome P450 family 11 subfamily A member 1* / Cholesterol side-chain cleavage enzyme, mitochondrial *ENSDARG0000000234718


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009410 response to xenobiotic stimulus IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Miscellaneous substrates
Xenobiotics
Aflatoxin activation and detoxification
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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