Manteia

ENSMUSG00000056035

Mus musculus

Features

Gene ID:	ENSMUSG00000056035

Biological name :	Cyp3a11

Synonyms :	Cyp3a11 / Cytochrome P450 3A11 / Q64459

Possible biological names infered from orthology :	CYP3A4 / CYP3A43 / CYP3A5 / CYP3A7 / CYP3A7-CYP3A51P / CYP3A7-CYP3A51P readthrough / cytochrome P450 family 3 subfamily A member 4 / cytochrome P450 family 3 subfamily A member 43 / cytochrome P450 family 3 subfamily A member 5 / cytochrome P450 family 3 subfamily A member 7 / P08684 / P20815 / P24462 / Q9HB55

Species:	Mus musculus

Chr. number:	5
Strand:	-1
Band:	G2
Gene start:	145854426
Gene end:	145879964

Corresponding Affymetrix probe sets:	10535704 (MoGene1.0st) 1416809_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000037665 NCBI entrez gene - 13112 See in Manteia. MGI - MGI:88609 RefSeq - NM_007818 RefSeq Peptide - NP_031844 swissprot - Q3UEN8 swissprot - Q64459 Ensembl - ENSMUSG00000056035

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
cyp3a65	ENSDARG00000103295	Danio rerio
cyp3c1	ENSDARG00000015575	Danio rerio
cyp3c2	ENSDARG00000037874	Danio rerio
cyp3c3	ENSDARG00000037873	Danio rerio
cyp3c4	ENSDARG00000070021	Danio rerio
CYP3A5	ENSGALG00000004449	Gallus gallus
CYP3A4	ENSG00000160868	Homo sapiens
CYP3A5	ENSG00000106258	Homo sapiens
CYP3A7	ENSG00000160870	Homo sapiens
P24462	ENSG00000282301	Homo sapiens
Q9HB55	ENSG00000021461	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Q9JMA7 / Cyp3a41a / Cytochrome P450 3A41 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readthrough* / cytochrome P45...	ENSMUSG00000075551	92
Q9JMA7 / Cyp3a41b / Cytochrome P450 3A41 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readthrough* / cytochrome P45...	ENSMUSG00000075552	92
Cyp3a44 / cytochrome P450, family 3, subfamily a, polypeptide 44 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readth...	ENSMUSG00000054417	90
Q64481 / Cyp3a16 / Cytochrome P450 3A16 / Q9HB55* / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readthrough* / cytochrome P450...	ENSMUSG00000038656	87
Q64464 / Cyp3a13 / Cytochrome P450 3A13 / Q9HB55* / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readthrough* / cytochrome P450...	ENSMUSG00000029727	71
O09158 / Cyp3a25 / Cytochrome P450 3A25 / Q9HB55* / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readthrough* / cytochrome P450...	ENSMUSG00000029630	70
Cyp3a59 / cytochrome P450, family 3, subfamily a, polypeptide 59 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readth...	ENSMUSG00000061292	68
Cyp3a57 / cytochrome P450, family 3, subfamily a, polypeptide 57 / CYP3A4* / CYP3A5* / CYP3A7* / P08684* / P20815* / P24462* / Q9HB55* / CYP3A43* / CYP3A7-CYP3A51P* / CYP3A7-CYP3A51P readth...	ENSMUSG00000070419	67
P36423 / Tbxas1 / thromboxane A synthase 1, platelet / P24557* / thromboxane A synthase 1*	ENSMUSG00000029925	35
Q9WVK8 / Cyp46a1 / Cholesterol 24-hydroxylase / Q9Y6A2* / cytochrome P450 family 46 subfamily A member 1*	ENSMUSG00000021259	25
Q9DBG1 / Cyp27a1 / Sterol 26-hydroxylase, mitochondrial / Q02318* / cytochrome P450 family 27 subfamily A member 1*	ENSMUSG00000026170	23
O35084 / Cyp27b1 / 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial / O15528* / cytochrome P450 family 27 subfamily B member 1*	ENSMUSG00000006724	22
Cyp11b2 / cytochrome P450, family 11, subfamily b, polypeptide 2 / P19099* / P15538* / CYP11B1* / cytochrome P450 family 11 subfamily B member 1* / cytochrome P450 family 11 subfamily B member 2*	ENSMUSG00000022589	21
Q9QZ82 / Cyp11a1 / Cholesterol side-chain cleavage enzyme, mitochondrial / P05108* / cytochrome P450 family 11 subfamily A member 1*	ENSMUSG00000032323	21
Cyp11b1 / cytochrome P450, family 11, subfamily b, polypeptide 1 / P15538* / P19099* / CYP11B2* / cytochrome P450 family 11 subfamily B member 2* / cytochrome P450 family 11 subfamily B member 1*	ENSMUSG00000075604	21
Q64441 / Cyp24a1 / 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial / Q07973* / cytochrome P450 family 24 subfamily A member 1*	ENSMUSG00000038567	20

Protein motifs (from Interpro)

Interpro ID	Name
IPR001128	Cytochrome P450
IPR002402	Cytochrome P450, E-class, group II
IPR008072	Cytochrome P450, E-class, CYP3A
IPR017972	Cytochrome P450, conserved site
IPR036396	Cytochrome P450 superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0055114	oxidation-reduction process	IEA
cellular_component	GO:0005783	endoplasmic reticulum	IEA
cellular_component	GO:0005789	endoplasmic reticulum membrane	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0031090	organelle membrane	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0004497	monooxygenase activity	IDA
molecular_function	GO:0005506	iron ion binding	IEA
molecular_function	GO:0016491	oxidoreductase activity	ISO
molecular_function	GO:0016705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA
molecular_function	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	IEA
molecular_function	GO:0020037	heme binding	IEA
molecular_function	GO:0046872	metal ion binding	IEA
molecular_function	GO:0070330	aromatase activity	IEA
molecular_function	GO:0101020	estrogen 16-alpha-hydroxylase activity	ISO

Pathways (from Reactome)

Pathway description

Miscellaneous substrates

Xenobiotics

Aflatoxin activation and detoxification

Biosynthesis of maresin-like SPMs

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0002966	decreased circulating alkaline phosphatase level	"reduced activity of this enzyme, which hydrolyzes orthophosphoric monoesters, found in the blood" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Clrn1^{tm1.1(KOMP)Vlcg}/Clrn1^{tm1.1(KOMP)Vlcg} Genetic Background: C57BL/6N-Clrn1^{tm1.1(KOMP)Vlcg}/Ucd

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2025 contact: otassy@igbmc.fr