ENSGALG00000004449


Gallus gallus

Features
Gene ID: ENSGALG00000004449
  
Biological name :CYP3A5
  
Synonyms : CYP3A5 / cytochrome P450 family 3 subfamily A member 5
  
Possible biological names infered from orthology : Cyp3a11 / Cyp3a13 / Cyp3a16 / Cyp3a25 / CYP3A4 / Cyp3a41a / Cyp3a41b / CYP3A43 / Cyp3a44 / Cyp3a57 / Cyp3a59 / CYP3A7 / CYP3A7-CYP3A51P / CYP3A7-CYP3A51P readthrough / Cytochrome P450 3A11 / Cytochrome P450 3A13 / Cytochrome P450 3A16 / Cytochrome P450 3A25 / Cytochrome P450 3A41 / cytochrome P450 family 3 subfamily A member 4 / cytochrome P450 family 3 subfamily A member 43 / cytochrome P450 family 3 subfamily A member 7 / cytochrome P450, family 3, subfamily a, polypeptide 44 / cytochrome P450, family 3, subfamily a, polypeptide 57 / cytochrome P450, family 3, subfamily a, polypeptide 59 / O09158 / P08684 / P20815 / P24462 / Q64459 / Q64464 / Q64481 / Q9HB55 / Q9JMA7
  
Species: Gallus gallus
  
Chr. number: 14
Strand: -1
Band:
Gene start: 3928052
Gene end: 3937393
  
Corresponding Affymetrix probe sets: Gga.1163.1.S1_at (Chicken Array)   GgaAffx.21825.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000007068
NCBI entrez gene - 414832     See in Manteia.
RefSeq - NM_001001751
RefSeq Peptide - NP_001001751
swissprot - F1NT18
Ensembl - ENSGALG00000004449
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp3a65ENSDARG00000103295Danio rerio
 cyp3c1ENSDARG00000015575Danio rerio
 cyp3c2ENSDARG00000037874Danio rerio
 cyp3c3ENSDARG00000037873Danio rerio
 cyp3c4ENSDARG00000070021Danio rerio
 CYP3A4ENSG00000160868Homo sapiens
 CYP3A5ENSG00000106258Homo sapiens
 CYP3A7ENSG00000160870Homo sapiens
 P24462ENSG00000282301Homo sapiens
 Q9HB55ENSG00000021461Homo sapiens
 Cyp3a44ENSMUSG00000054417Mus musculus
 Cyp3a57ENSMUSG00000070419Mus musculus
 Cyp3a59ENSMUSG00000061292Mus musculus
 O09158ENSMUSG00000029630Mus musculus
 Q64459ENSMUSG00000056035Mus musculus
 Q64464ENSMUSG00000029727Mus musculus
 Q64481ENSMUSG00000038656Mus musculus
 Q9JMA7ENSMUSG00000075552Mus musculus
 Q9JMA7ENSMUSG00000075551Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CYP3A4 / Gallus gallus cytochrome P450 family 3 subfamily A member 4 (CYP3A4), mRNA.ENSGALG0000000443661
TBXAS1 / thromboxane A synthase 1 / P24557* / P36423* / thromboxane A synthase 1, platelet*ENSGALG0000001279134
Q4G0S4* / CYP27C1* / cytochrome P450 family 27 subfamily C member 1*ENSGALG0000001153224
CYP46A1 / cytochrome P450 family 46 subfamily A member 1 / Q9WVK8* / Q9Y6A2* / Cholesterol 24-hydroxylase *ENSGALG0000001116223
CYP27A1 / cytochrome P450 family 27 subfamily A member 1 / Q02318* / Q9DBG1* / Sterol 26-hydroxylase, mitochondrial *ENSGALG0000000247019
CYP24A1 / 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial / Q07973* / Q64441* / cytochrome P450 family 24 subfamily A member 1*ENSGALG0000004227919
CYP11A1 / cholesterol side-chain cleavage enzyme, mitochondrial / P05108* / Q9QZ82* / cytochrome P450 family 11 subfamily A member 1*ENSGALG0000003498217


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002402  Cytochrome P450, E-class, group II
 IPR008072  Cytochrome P450, E-class, CYP3A
 IPR017972  Cytochrome P450, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008202 steroid metabolic process IDA
 biological_processGO:0017144 drug metabolic process IMP
 biological_processGO:0042445 hormone metabolic process IDA
 biological_processGO:0042448 progesterone metabolic process IDA
 biological_processGO:0043385 mycotoxin metabolic process IDA
 biological_processGO:0046677 response to antibiotic IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0070988 demethylation IEA
 biological_processGO:1901615 organic hydroxy compound metabolic process IDA
 cellular_componentGO:0005623 cell IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IDA
 cellular_componentGO:0045177 apical part of cell IDA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0032451 demethylase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050649 testosterone 6-beta-hydroxylase activity IDA


Pathways (from Reactome)
Pathway description
Miscellaneous substrates
Xenobiotics
Aflatoxin activation and detoxification
Biosynthesis of maresin-like SPMs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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