ENSDARG00000052898


Danio rerio

Features
Gene ID: ENSDARG00000052898
  
Biological name :kcnk3b
  
Synonyms : kcnk3b / potassium channel, subfamily K, member 3b
  
Possible biological names infered from orthology : KCNK3 / O14649 / O35111 / Potassium channel subfamily K member 3 / potassium two pore domain channel subfamily K member 3
  
Species: Danio rerio
  
Chr. number: 17
Strand: 1
Band:
Gene start: 45454943
Gene end: 45459207
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000069324
NCBI entrez gene - 571330     See in Manteia.
RefSeq - XM_694909
swissprot - E7F9D1
ZFIN ID - ZDB-GENE-120709-43
Ensembl - ENSDARG00000052898
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KCNK3ENSGALG00000025971Gallus gallus
 KCNK3ENSG00000171303Homo sapiens
 Kcnk3ENSMUSG00000049265Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
kcnk3a / potassium channel, subfamily K, member 3a / KCNK3* / O35111* / O14649* / Potassium channel subfamily K member 3 * / potassium two pore domain channel subfamily K member 3*ENSDARG0000004346669
kcnk9 / potassium channel, subfamily K, member 9 / Q3LS21* / Q9NPC2* / potassium two pore domain channel subfamily K member 9*ENSDARG0000010456357
kcnk15 / potassium channel, subfamily K, member 15 / Q9H427* / potassium two pore domain channel subfamily K member 15*ENSDARG0000007737151
kcnk10a / potassium channel, subfamily K, member 10a / P57789* / KCNK10* / potassium channel, subfamily K, member 10* / potassium two pore domain channel subfamily K member 10*ENSDARG0000006284925
kcnk10b / potassium channel, subfamily K, member 10b / P57789* / KCNK10* / potassium channel, subfamily K, member 10* / potassium two pore domain channel subfamily K member 10*ENSDARG0000004595624
kcnk2a / potassium channel, subfamily K, member 2a / KCNK2* / O95069* / P97438* / potassium two pore domain channel subfamily K member 2* / Mus musculus potassium channel, subfamily K, memb...ENSDARG0000005512323
kcnk2b / potassium channel, subfamily K, member 2b / KCNK2* / O95069* / P97438* / potassium two pore domain channel subfamily K member 2* / Mus musculus potassium channel, subfamily K, memb...ENSDARG0000000715122
kcnk5b / potassium channel, subfamily K, member 5bENSDARG0000001239021
kcnk1b / potassium channel, subfamily K, member 1b / KCNK1* / O08581* / O00180* / Potassium channel subfamily K member 1 * / potassium two pore domain channel subfamily K member 1*ENSDARG0000001725421
kcnk4a / potassium channel, subfamily K, member 4a / KCNK4* / Q9NYG8* / O88454* / Potassium channel subfamily K member 4 * / potassium two pore domain channel subfamily K member 4*ENSDARG0000010328621
kcnk17 / potassium channel, subfamily K, member 17 / Q96T54* / potassium two pore domain channel subfamily K member 17*ENSDARG0000010545321
kcnk6 / potassium channel, subfamily K, member 6 / Q9Y257* / potassium two pore domain channel subfamily K member 6* / potassium inwardly-rectifying channel, subfamily K, member 6*ENSDARG0000000738320
kcnk5a / potassium channel, subfamily K, member 5a / KCNK5* / O95279* / potassium two pore domain channel subfamily K member 5*ENSDARG0000002358720
kcnk1a / potassium channel, subfamily K, member 1a / KCNK1* / O08581* / O00180* / Potassium channel subfamily K member 1 * / potassium two pore domain channel subfamily K member 1*ENSDARG0000004506720
kcnk7 / potassium channel, subfamily K, member 7 / Q9Y2U2* / potassium two pore domain channel subfamily K member 7*ENSDARG0000005733118


Protein motifs (from Interpro)
Interpro ID Name
 IPR003092  Two pore domain potassium channel, TASK family
 IPR003280  Two pore domain potassium channel
 IPR005406  Potassium channel subfamily K member 3
 IPR013099  Potassium channel domain
 IPR022341  Insulin-like growth factor I


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030322 stabilization of membrane potential IBA
 biological_processGO:0060047 heart contraction IGI
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005252 open rectifier potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0022841 potassium ion leak channel activity IBA


Pathways (from Reactome)
Pathway description
TWIK-releated acid-sensitive K+ channel (TASK)
Phase 4 - resting membrane potential


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000114 heart heart morphology , abnormal
Show

 ZFA:0000471 atrium atrium decreased functionality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000052898 kcnk3b / potassium channel, subfamily K, member 3b / KCNK3* / O35111* / O14649* / Potassium channel subfamily K member 3 * / potassium two pore domain channel subfamily K member 3*  / complex
 ENSDARG00000043466 kcnk3a / potassium channel, subfamily K, member 3a / KCNK3* / O35111* / O14649* / Potassium channel subfamily K member 3 * / potassium two pore domain channel subfamily K member 3*  / complex






 

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