ENSDARG00000054937


Danio rerio

Features
Gene ID: ENSDARG00000054937
  
Biological name :badb
  
Synonyms : badb / BCL2 associated agonist of cell death b
  
Possible biological names infered from orthology : BAD / BCL2 associated agonist of cell death / Q61337 / Q92934
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 25129520
Gene end: 25133853
  
Corresponding Affymetrix probe sets: Dr.28.1.S1_at (Zebrafish Array)   Dr.28.2.A1_at (Zebrafish Array)   NM_131579_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000071687
Ensembl peptide - ENSDARP00000106381
Ensembl peptide - ENSDARP00000142822
Ensembl peptide - ENSDARP00000155309
NCBI entrez gene - 58100     See in Manteia.
RefSeq - NM_131579
RefSeq - NM_001270595
RefSeq - XM_005172305
RefSeq Peptide - NP_571654
RefSeq Peptide - NP_001257524
swissprot - Q4V925
swissprot - Q9I9N2
ZFIN ID - ZDB-GENE-000616-1
Ensembl - ENSDARG00000054937
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 BADENSG00000002330Homo sapiens
 BadENSMUSG00000024959Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
bada / BCL2 associated agonist of cell death a / BAD* / Q92934* / BCL2 associated agonist of cell death*ENSDARG0000008799329


Protein motifs (from Interpro)
Interpro ID Name
 IPR018868  Bcl2-associated agonist of cell death


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process IGI
 biological_processGO:0071479 cellular response to ionizing radiation IMP
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA


Pathways (from Reactome)
Pathway description
Activation of BAD and translocation to mitochondria
BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain apoptotic process decreased process quality , abnormal
Show

 ZFA:0000075 spinal cord spinal cord apoptotic process decreased process quality , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000057456 ppp3ccb / protein phosphatase 3, catalytic subunit, gamma isozyme, b / P48455* / PPP3CC* / P48454* / protein phosphatase 3 catalytic subunit gamma* / protein phosphatase 3, catalytic subuni...  / reaction
 ENSDARG00000008434 bcl2l1 / bcl2-like 1 / Q07817* / Q64373* / Mus musculus BCL2-like 1 (Bcl2l1), transcript variant 5, mRNA.*  / complex / reaction
 ENSDARG00000069360 ppp3r1b / protein phosphatase 3 (formerly 2B), regulatory s1ubunit B, alpha isoform, b / PPP3R1* / P63098* / Q63810* / protein phosphatase 3 regulatory subunit B, alpha* / protein phosphata...  / reaction
 ENSDARG00000014962 ppp3cca / protein phosphatase 3, catalytic subunit, gamma isozyme, a / P48455* / PPP3CC* / P48454* / protein phosphatase 3 catalytic subunit gamma* / protein phosphatase 3, catalytic subuni...  / reaction






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr