ENSDARG00000055750


Danio rerio

Features
Gene ID: ENSDARG00000055750
  
Biological name :foxp3a
  
Synonyms : forkhead box P3a / foxp3a
  
Possible biological names infered from orthology : forkhead box P3 / Forkhead box protein P3 Forkhead box protein P3, C-terminally processed Forkhead box protein P3 41 kDa form / FOXP3 / Q99JB6 / Q9BZS1
  
Species: Danio rerio
  
Chr. number: 8
Strand: -1
Band:
Gene start: 25716308
Gene end: 25729543
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000072611
Ensembl peptide - ENSDARP00000108584
Ensembl peptide - ENSDARP00000080214
NCBI entrez gene - 571165     See in Manteia.
RefSeq - NM_001329567
RefSeq - XM_021478298
RefSeq Peptide - NP_001316496
swissprot - A1L5C8
swissprot - D2EAB6
swissprot - A8WFW7
ZFIN ID - ZDB-GENE-061116-2
Ensembl - ENSDARG00000055750
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 FOXP3ENSG00000049768Homo sapiens
 Foxp3ENSMUSG00000039521Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
foxp2 / forkhead box P2ENSDARG0000000545337
foxp1b / forkhead box P1b / Foxp1* / P58462* / Mus musculus forkhead box P1 (Foxp1), transcript variant 4, mRNA.*ENSDARG0000001418136
foxp4 / forkhead box P4ENSDARG0000007612035
foxp1a / forkhead box P1aENSDARG0000000484334
foxp3b / forkhead box P3b / FOXP3* / Q99JB6* / Q9BZS1* / forkhead box P3* / Forkhead box protein P3 Forkhead box protein P3, C-terminally processed Forkhead box protein P3 41 kDa form*ENSDARG0000007827930
foxf1 / A1L1S5 / forkhead box F1 / Q61080* / Q12946* / Forkhead box protein F1 *ENSDARG0000001539912
foxd3 / forkhead box D3 / FOXD4* / Q9UJU5* / Q12950* / Q3SYB3* / Q5VV16* / Q60688* / Q6VB84* / Q8WXT5* / Q9NU39* / FOXD4L3* / FOXD4L4* / FOXD4L5* / FOXD4L6* / FOXD4L1* / forkhead box D4* / ...ENSDARG0000002103212
foxd2 / forkhead box D2 / FOXD1* / O35392* / O60548* / Q16676* / Q61345* / forkhead box D1* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000005813312
foxf2b / forkhead box F2b / FOXF2* / O54743* / Q12947* / forkhead box F2* / Forkhead box protein F2 *ENSDARG0000007038912
foxg1a / forkhead box G1a / FOXG1* / P55316* / Q60987* / Gm43517* / forkhead box G1* / Forkhead box protein G1 *ENSDARG0000007076912
foxf2a / forkhead box F2a / FOXF2* / O54743* / Q12947* / forkhead box F2* / Forkhead box protein F2 *ENSDARG0000001719511
foxd1 / forkhead box D1 / FOXD2* / Q61345* / O35392* / O60548* / Q16676* / forkhead box D2* / Forkhead box protein D2 * / Forkhead box protein D1 *ENSDARG0000002917911
foxg1b / forkhead box G1bENSDARG0000003270511
foxe3 / forkhead box E3 / FOXE1* / O00358* / Q13461* / Q8R2I0* / Q9QY14* / forkhead box E1* / Forkhead box protein E1 * / Forkhead box protein E3 *ENSDARG0000006289211
foxg1c / forkhead box G1cENSDARG0000006838011
foxg1d / forkhead box G1dENSDARG0000007005311
zgc:162612 / FOXD1* / FOXD2* / O60548* / Q61345* / Q16676* / O35392* / forkhead box D1* / forkhead box D2* / Forkhead box protein D1 * / Forkhead box protein D2 *ENSDARG0000007969911
foxh1 / forkhead box H1 / O75593* / O88621* / Forkhead box protein H1 *ENSDARG0000005563010
foxq2 / forkhead box Q2ENSDARG0000007139410
foxe1 / forkhead box E1 / FOXE3* / Q9QY14* / O00358* / Q13461* / Q8R2I0* / forkhead box E3* / Forkhead box protein E3 * / Forkhead box protein E1 *ENSDARG0000007926610


Protein motifs (from Interpro)
Interpro ID Name
 IPR001766  Fork head domain
 IPR011991  ArsR-like helix-turn-helix domain
 IPR030456  Fork head domain conserved site 2
 IPR032354  FOXP, coiled-coil domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0042129 regulation of T cell proliferation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000056 pharynx pharynx inflammatory , abnormal
pharynx has extra parts of type T cell , abnormal
pharynx T cell increased amount , abnormal
Show

 ZFA:0000354 gill gill inflammatory , abnormal
gill has extra parts of type T cell , abnormal
Show

 ZFA:0000368 integument integument inflammatory , abnormal
integument has extra parts of type T cell , abnormal
integument T cell increased amount , abnormal
Show

 ZFA:0000554 olfactory epithelium olfactory epithelium inflammatory , abnormal
olfactory epithelium has extra parts of type T cell , abnormal
olfactory epithelium T cell increased amount , abnormal
Show

 ZFA:0000667 gill filament gill filament swollen , abnormal
gill filament T cell increased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism increased amount , abnormal
whole organism viability , abnormal
whole organism decreased length , abnormal
whole organism decreased weight , abnormal
Show

 ZFA:0001338 intestine intestine swollen , abnormal
intestine has extra parts of type T cell , abnormal
intestine T cell increased amount , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr