ENSDARG00000056795


Danio rerio

Features
Gene ID: ENSDARG00000056795
  
Biological name :serpine1
  
Synonyms : serpine1 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  
Possible biological names infered from orthology : P05121 / serine (or cysteine) peptidase inhibitor, clade E, member 1 / serpin family E member 1
  
Species: Danio rerio
  
Chr. number: 7
Strand: -1
Band:
Gene start: 26265584
Gene end: 26270014
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSDARP00000073803
NCBI entrez gene - 100136840     See in Manteia.
RefSeq - NM_001114559
RefSeq Peptide - NP_001108031
swissprot - F1QRB8
ZFIN ID - ZDB-GENE-070912-60
Ensembl - ENSDARG00000056795
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 P05121ENSG00000106366Homo sapiens
 Serpine1ENSMUSG00000037411Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
serpine2 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 / P07093* / serpin family E member 2*ENSDARG0000002935336
serpini1 / serpin peptidase inhibitor, clade I (neuroserpin), member 1 / O35684* / Q99574* / serpin family I member 1* / serine (or cysteine) peptidase inhibitor, clade I, member 1*ENSDARG0000003416830
B0UYL8 / serpine3 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 / A8MV23* / serpin family E member 3*ENSDARG0000005710828
serpinc1 / serpin peptidase inhibitor, clade C (antithrombin), member 1 / P01008* / P32261* / serpin family C member 1* / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1*ENSDARG0000004268426
serpinh1b / serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b / P50454* / P19324* / SERPINH1* / Serpin H1 * / serpin family H member 1*ENSDARG0000001994922
serpinh2 / serine (or cysteine) peptidase inhibitor, clade H, member 2ENSDARG0000003644522
serpinh1a / serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a / P50454* / P19324* / SERPINH1* / Serpin H1 * / serpin family H member 1*ENSDARG0000007595421


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023796  Serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010757 negative regulation of plasminogen activation IDA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IDA


Pathways (from Reactome)
Pathway description
Platelet degranulation
ECM proteoglycans
Dissolution of Fibrin Clot


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000053831 vtnb / vitronectin b / VTN* / P04004* / P29788* / AC002094.3* / vitronectin*  / complex / reaction
 ENSDARG00000062707 plat / plasminogen activator, tissue / P11214* / P00750* / plasminogen activator, tissue type* / Tissue-type plasminogen activator Tissue-type plasminogen activator chain A Tissue-type plas...  / complex / reaction






 

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