ENSDARG00000029353


Danio rerio

Features
Gene ID: ENSDARG00000029353
  
Biological name :serpine2
  
Synonyms : serpine2 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
  
Possible biological names infered from orthology : P07093 / Q07235 / serine (or cysteine) peptidase inhibitor, clade E, member 2 / serpin family E member 2
  
Species: Danio rerio
  
Chr. number: 15
Strand: -1
Band:
Gene start: 43241915
Gene end: 43284021
  
Corresponding Affymetrix probe sets: Dr.10097.1.S1_at (Zebrafish Array)   NM_200184_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000041676
Ensembl peptide - ENSDARP00000131823
NCBI entrez gene - 393153     See in Manteia.
RefSeq - NM_200184
RefSeq Peptide - NP_956478
swissprot - Q7ZVL5
ZFIN ID - ZDB-GENE-040426-848
Ensembl - ENSDARG00000029353
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SERPINE2ENSGALG00000005135Gallus gallus
 P07093ENSG00000135919Homo sapiens
 Q07235ENSMUSG00000026249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
serpine1 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 / P05121* / serpin family E member 1* / serine (or cysteine) peptidase inhibitor, cl...ENSDARG0000005679536
serpini1 / serpin peptidase inhibitor, clade I (neuroserpin), member 1 / O35684* / Q99574* / serpin family I member 1* / serine (or cysteine) peptidase inhibitor, clade I, member 1*ENSDARG0000003416832
B0UYL8 / serpine3 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3 / A8MV23* / serpin family E member 3*ENSDARG0000005710830
serpinc1 / serpin peptidase inhibitor, clade C (antithrombin), member 1 / P01008* / P32261* / serpin family C member 1* / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1*ENSDARG0000004268427
serpinh1b / serpin peptidase inhibitor, clade H (heat shock protein 47), member 1b / P50454* / P19324* / SERPINH1* / Serpin H1 * / serpin family H member 1*ENSDARG0000001994923
serpinh2 / serine (or cysteine) peptidase inhibitor, clade H, member 2ENSDARG0000003644522
serpinh1a / serpin peptidase inhibitor, clade H (heat shock protein 47), member 1a / P50454* / P19324* / SERPINH1* / Serpin H1 * / serpin family H member 1*ENSDARG0000007595422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IBA


Pathways (from Reactome)
Pathway description
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
Dissolution of Fibrin Clot


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000029353 serpine2 / serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 / P07093* / serpin family E member 2*  / complex
 ENSDARG00000036041 f2 / coagulation factor II (thrombin) / P00734* / P19221* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction






 

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