ENSGALG00000005135


Gallus gallus

Features
Gene ID: ENSGALG00000005135
  
Biological name :SERPINE2
  
Synonyms : SERPINE2 / serpin family E member 2
  
Possible biological names infered from orthology : P07093 / Q07235 / serine (or cysteine) peptidase inhibitor, clade E, member 2
  
Species: Gallus gallus
  
Chr. number: 9
Strand: -1
Band:
Gene start: 8320170
Gene end: 8343285
  
Corresponding Affymetrix probe sets: Gga.4105.2.S1_a_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000051896
Ensembl peptide - ENSGALP00000053708
Ensembl peptide - ENSGALP00000008232
NCBI entrez gene - 424805     See in Manteia.
RefSeq - XM_015276900
RefSeq - XM_015276897
RefSeq - XM_015276898
RefSeq - XM_015276899
RefSeq - NM_001083920
RefSeq - XM_015276895
RefSeq - XM_015276896
RefSeq Peptide - NP_001077389
swissprot - E1BWU2
swissprot - A0A1D5PLJ1
Ensembl - ENSGALG00000005135
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serpine2ENSDARG00000029353Danio rerio
 P07093ENSG00000135919Homo sapiens
 Q07235ENSMUSG00000026249Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q90935 / SERPINI1 / Neuroserpin / O35684* / Q99574* / serpin family I member 1* / serine (or cysteine) peptidase inhibitor, clade I, member 1*ENSGALG0000000947030
SERPINE3 / serpin family E member 3 / A8MV23*ENSGALG0000001701729
SERPINB12 / serpin family B member 12 / Q96P63* / Q9D7P9* / Serpin B12 *ENSGALG0000001287228
SERPINC1 / Gallus gallus serpin family C member 1 (SERPINC1), mRNA. / P32261* / P01008* / serpin family C member 1* / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1*ENSGALG0000000459126
OVAL / P01012 / Ovalbumin / Q9D695* / O75635* / Q96P15* / Q9CQV3* / SERPINB7* / SERPINB11* / Serpin B7 * / Serpin B11 * / serpin family B member 7* / serpin family B member 11 (gene/pseudogene)*ENSGALG0000001286924
OVALY / ovalbumin-related protein Y / Q9CQV3* / Q9D695* / O75635* / Q96P15* / SERPINB7* / SERPINB11* / Serpin B7 * / Serpin B11 * / serpin family B member 7* / serpin family B member 11 (g...ENSGALG0000001955124
OVALX / O75635* / Q96P15* / Q9CQV3* / Q9D695* / SERPINB7* / SERPINB11* / Serpin B7 * / Serpin B11 * / serpin family B member 7* / serpin family B member 11 (gene/pseudogene)*ENSGALG0000004325224
P13731 / SERPINH1 / Serpin H1 / P50454* / P19324* / serpin family H member 1*ENSGALG0000001121421


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0009611 response to wounding IEA
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010544 negative regulation of platelet activation IEA
 biological_processGO:0010757 negative regulation of plasminogen activation IEA
 biological_processGO:0010766 negative regulation of sodium ion transport IEA
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0021683 cerebellar granular layer morphogenesis IEA
 biological_processGO:0030195 negative regulation of blood coagulation IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:0032940 secretion by cell IEA
 biological_processGO:0033363 secretory granule organization IEA
 biological_processGO:0042177 negative regulation of protein catabolic process IEA
 biological_processGO:0042628 mating plug formation IEA
 biological_processGO:0045861 negative regulation of proteolysis IEA
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IEA
 biological_processGO:0048505 regulation of timing of cell differentiation IEA
 biological_processGO:0048711 positive regulation of astrocyte differentiation IEA
 biological_processGO:0050974 detection of mechanical stimulus involved in sensory perception IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060291 long-term synaptic potentiation IEA
 biological_processGO:0060384 innervation IEA
 biological_processGO:0061108 seminal vesicle epithelium development IEA
 biological_processGO:0090331 negative regulation of platelet aggregation IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 cellular_componentGO:0031091 platelet alpha granule IEA
 cellular_componentGO:0031232 extrinsic component of external side of plasma membrane IEA
 cellular_componentGO:0031594 neuromuscular junction IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005539 glycosaminoglycan binding IEA
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008332 F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction
 ENSGALG00000005135 SERPINE2 / serpin family E member 2 / P07093* / Q07235* / serine (or cysteine) peptidase inhibitor, clade E, member 2*  / complex






 

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