ENSGALG00000004591


Gallus gallus

Features
Gene ID: ENSGALG00000004591
  
Biological name :SERPINC1
  
Synonyms : Gallus gallus serpin family C member 1 (SERPINC1), mRNA. / SERPINC1
  
Possible biological names infered from orthology : P01008 / P32261 / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 / serpin family C member 1
  
Species: Gallus gallus
  
Chr. number: 8
Strand: 1
Band:
Gene start: 7408662
Gene end: 7414693
  
Corresponding Affymetrix probe sets: Gga.4453.1.S1_at (Chicken Array)   Gga.825.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064690
Ensembl peptide - ENSGALP00000007292
NCBI entrez gene - 424440     See in Manteia.
RefSeq - XM_422282
RefSeq - NM_001353945
RefSeq Peptide - NP_001340874
swissprot - A0A1L1S0N7
swissprot - F1NLP7
Ensembl - ENSGALG00000004591
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 serpinc1ENSDARG00000042684Danio rerio
 P01008ENSG00000117601Homo sapiens
 P32261ENSMUSG00000026715Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SERPINB12 / serpin family B member 12 / Q96P63* / Q9D7P9* / Serpin B12 *ENSGALG0000001287230
OVALY / ovalbumin-related protein Y / Q9CQV3* / Q9D695* / O75635* / Q96P15* / SERPINB7* / SERPINB11* / Serpin B7 * / Serpin B11 * / serpin family B member 7* / serpin family B member 11 (g...ENSGALG0000001955128
OVALX / O75635* / Q96P15* / Q9CQV3* / Q9D695* / SERPINB7* / SERPINB11* / Serpin B7 * / Serpin B11 * / serpin family B member 7* / serpin family B member 11 (gene/pseudogene)*ENSGALG0000004325228
Q90935 / SERPINI1 / Neuroserpin / O35684* / Q99574* / serpin family I member 1* / serine (or cysteine) peptidase inhibitor, clade I, member 1*ENSGALG0000000947027
OVAL / P01012 / Ovalbumin / Q9D695* / O75635* / Q96P15* / Q9CQV3* / SERPINB7* / SERPINB11* / Serpin B7 * / Serpin B11 * / serpin family B member 7* / serpin family B member 11 (gene/pseudogene)*ENSGALG0000001286926
SERPINE2 / serpin family E member 2 / P07093* / Q07235* / serine (or cysteine) peptidase inhibitor, clade E, member 2*ENSGALG0000000513525
SERPINE3 / serpin family E member 3 / A8MV23*ENSGALG0000001701724
P13731 / SERPINH1 / Serpin H1 / P50454* / P19324* / serpin family H member 1*ENSGALG0000001121423


Protein motifs (from Interpro)
Interpro ID Name
 IPR000215  Serpin family
 IPR015555  Antithrombin-III
 IPR023795  Serpin, conserved site
 IPR023796  Serpin domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010951 negative regulation of endopeptidase activity IEA
 biological_processGO:0030193 regulation of blood coagulation IEA
 biological_processGO:2000266 regulation of blood coagulation, intrinsic pathway IEA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0002020 protease binding IEA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity IEA
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000004591 SERPINC1 / Gallus gallus serpin family C member 1 (SERPINC1), mRNA. / P32261* / P01008* / serpin family C member 1* / serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1*  / complex
 ENSGALG00000008332 F2 / prothrombin precursor / P00734* / P19221* / coagulation factor II, thrombin* / Prothrombin Activation peptide fragment 1 Activation peptide fragment 2 Thrombin light chain Thrombin heavy chain*  / complex / reaction






 

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